Osborn Maire相关文献与解析，生知库 | 链接生命科学的每一步

Novel Cluster and Monomer-Based GalNAc Structures Induce Effective Uptake of siRNAs in Vitro and in Vivo

新型簇状和单体状 GalNAc 结构可诱导 siRNA 在体外和体内的有效吸收

doi:10.1021/acs.bioconjchem.8b00365

Sharma, Vivek K; Osborn, Maire F; Hassler, Matthew R; Echeverria, Dimas; Ly, Socheata; Ulashchik, Egor A; Martynenko-Makaev, Yury V; Shmanai, Vadim V; Zatsepin, Timofei S; Khvorova, Anastasia; Watts, Jonathan K

发表日期：2018

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Synthesis and Evaluation of Parenchymal Retention and Efficacy of a Metabolically Stable O-Phosphocholine-N-docosahexaenoyl-l-serine siRNA Conjugate in Mouse Brain.

合成和评价代谢稳定的 O-磷酸胆碱-N-二十二碳六烯酰-L-丝氨酸 siRNA 缀合物在小鼠脑中的实质保留和功效

期刊:Bioconjugate Chemistry

影响因子:3.9

doi:10.1021/acs.bioconjchem.7b00226

Nikan Mehran, Osborn Maire F, Coles Andrew H, Biscans Annabelle, Godinho Bruno M D C, Haraszti Reka A, Sapp Ellen, Echeverria Dimas, DiFiglia Marian, Aronin Neil, Khvorova Anastasia

Docosahexaenoic Acid Conjugation Enhances Distribution and Safety of siRNA upon Local Administration in Mouse Brain

二十二碳六烯酸偶联可增强siRNA在小鼠脑内局部给药后的分布和安全性

期刊:Molecular Therapy-Nucleic Acids

影响因子:6.1

doi:10.1038/mtna.2016.50

Nikan, Mehran; Osborn, Maire F; Coles, Andrew H; Godinho, Bruno Mdc; Hall, Lauren M; Haraszti, Reka A; Hassler, Matthew R; Echeverria, Dimas; Aronin, Neil; Khvorova, Anastasia

A High-Throughput Method for Direct Detection of Therapeutic Oligonucleotide-Induced Gene Silencing In Vivo

一种用于直接检测体内治疗性寡核苷酸诱导基因沉默的高通量方法

期刊:Nucleic Acid Therapeutics

影响因子:4.7

doi:10.1089/nat.2015.0578

Coles, Andrew H; Osborn, Maire F; Alterman, Julia F; Turanov, Anton A; Godinho, Bruno M D C; Kennington, Lori; Chase, Kathryn; Aronin, Neil; Khvorova, Anastasia

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发表日期：2016

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Platinum-RNA modifications following drug treatment in S. cerevisiae identified by click chemistry and enzymatic mapping

利用点击化学和酶图谱鉴定酿酒酵母药物处理后铂-RNA修饰。

期刊:ACS Chemical Biology

影响因子:3.8

doi:10.1021/cb500395z

Osborn, Maire F; White, Jonathan D; Haley, Michael M; DeRose, Victoria J

发表日期：2014

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Picazoplatin, an azide-containing platinum(II) derivative for target analysis by click chemistry

吡卡唑铂，一种含叠氮基的铂(II)衍生物，可用于点击化学靶向分析。

期刊:Journal of the American Chemical Society

影响因子:15.6

doi:10.1021/ja402453k

White, Jonathan D; Osborn, Maire F; Moghaddam, Alan D; Guzman, Lindsay E; Haley, Michael M; DeRose, Victoria J

发表日期：2013

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Binding of kinetically inert metal ions to RNA: the case of platinum(II)

动力学惰性金属离子与RNA的结合：以铂(II)为例

期刊:

影响因子:

doi:10.1039/9781849732512-00347

Chapman, Erich G; Hostetter, Alethia A; Osborn, Maire F; Miller, Amanda L; DeRose, Victoria J

发表日期：2011

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Diverse lipid conjugates for functional extra-hepatic siRNA delivery in vivo.

用于体内功能性肝外siRNA递送的多种脂质缀合物

Improving siRNA Delivery In Vivo Through Lipid Conjugation

通过脂质偶联改善体内siRNA递送

Novel Cluster and Monomer-Based GalNAc Structures Induce Effective Uptake of siRNAs in Vitro and in Vivo

新型簇状和单体状 GalNAc 结构可诱导 siRNA 在体外和体内的有效吸收

Synthesis and Evaluation of Parenchymal Retention and Efficacy of a Metabolically Stable O-Phosphocholine-N-docosahexaenoyl-l-serine siRNA Conjugate in Mouse Brain.

合成和评价代谢稳定的 O-磷酸胆碱-N-二十二碳六烯酰-L-丝氨酸 siRNA 缀合物在小鼠脑中的实质保留和功效

Docosahexaenoic Acid Conjugation Enhances Distribution and Safety of siRNA upon Local Administration in Mouse Brain

二十二碳六烯酸偶联可增强siRNA在小鼠脑内局部给药后的分布和安全性

A High-Throughput Method for Direct Detection of Therapeutic Oligonucleotide-Induced Gene Silencing In Vivo

一种用于直接检测体内治疗性寡核苷酸诱导基因沉默的高通量方法

Platinum-RNA modifications following drug treatment in S. cerevisiae identified by click chemistry and enzymatic mapping

利用点击化学和酶图谱鉴定酿酒酵母药物处理后铂-RNA修饰。

Picazoplatin, an azide-containing platinum(II) derivative for target analysis by click chemistry

吡卡唑铂，一种含叠氮基的铂(II)衍生物，可用于点击化学靶向分析。

Binding of kinetically inert metal ions to RNA: the case of platinum(II)

动力学惰性金属离子与RNA的结合：以铂(II)为例