Osenkowski Pamela相关文献与解析，生知库 | 链接生命科学的每一步

日期影响因子

Part 1: Notch-sparing γ-secretase inhibitors: The identification of novel naphthyl and benzofuranyl amide analogs

第一部分：不影响Notch通路γ-分泌酶的抑制剂：新型萘基和苯并呋喃基酰胺类似物的鉴定

期刊:Bioorganic & Medicinal Chemistry Letters

影响因子:2.2

doi:10.1016/j.bmcl.2016.03.040

Lu, Dai; Wei, Han-Xun; Zhang, Jing; Gu, Yongli; Osenkowski, Pamela; Ye, Wenjuan; Selkoe, Dennis J; Wolfe, Michael S; Augelli-Szafran, Corinne E

发表日期：2016

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Part 2. Notch-sparing γ-secretase inhibitors: The study of novel γ-amino naphthyl alcohols

第二部分：不影响Notch通路的γ-分泌酶抑制剂：新型γ-氨基萘醇的研究

期刊:Bioorganic & Medicinal Chemistry Letters

影响因子:2.2

doi:10.1016/j.bmcl.2016.03.042

Wei, Han-Xun; Lu, Dai; Sun, Vivien; Zhang, Jing; Gu, Yongli; Osenkowski, Pamela; Ye, Wenjuan; Selkoe, Dennis J; Wolfe, Michael S; Augelli-Szafran, Corinne E

发表日期：2016

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Dissociation between the processivity and total activity of γ-secretase: implications for the mechanism of Alzheimer's disease-causing presenilin mutations

γ-分泌酶的加工活性与总活性之间的分离：对阿尔茨海默病致病早老素突变机制的启示

期刊:Biochemistry

doi:10.1021/bi2007146

Quintero-Monzon, Omar; Martin, Morgan M; Fernandez, Marty A; Cappello, Christina A; Krzysiak, Amanda J; Osenkowski, Pamela; Wolfe, Michael S

阿尔茨海默症

发表日期：2011

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Cryoelectron microscopy structure of purified gamma-secretase at 12 A resolution.

纯化γ-分泌酶的冷冻电镜结构，分辨率为12 Å

期刊:Journal of Molecular Biology

影响因子:4.5

doi:10.1016/j.jmb.2008.10.078

Osenkowski Pamela, Li Hua, Ye Wenjuan, Li Dongyang, Aeschbach Lorene, Fraering Patrick C, Wolfe Michael S, Selkoe Dennis J, Li Huilin

免疫/内分泌

发表日期：2009

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Direct and potent regulation of gamma-secretase by its lipid microenvironment

脂质微环境对γ-分泌酶的直接而有效的调控

期刊:Journal of Biological Chemistry

影响因子:3.9

doi:10.1074/jbc.M801925200

Osenkowski, Pamela; Ye, Wenjuan; Wang, Rong; Wolfe, Michael S; Selkoe, Dennis J

发表日期：2008

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SPARC upregulates MT1-MMP expression, MMP-2 activation, and the secretion and cleavage of galectin-3 in U87MG glioma cells

SPARC 上调 U87MG 胶质瘤细胞中 MT1-MMP 的表达、MMP-2 的激活以及半乳糖凝集素-3 的分泌和裂解。

期刊:Neuroscience Letters

doi:10.1016/j.neulet.2007.04.037

McClung, Heather M; Thomas, Stacey L; Osenkowski, Pamela; Toth, Marta; Menon, Priya; Raz, Avraham; Fridman, Rafael; Rempel, Sandra A

多发性骨髓瘤

细胞生物学

发表日期：2007

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Cleavage at the stem region releases an active ectodomain of the membrane type 1 matrix metalloproteinase

茎区切割释放出膜型1基质金属蛋白酶的活性胞外结构域

期刊:Biochemical Journal

影响因子:4.3

doi:10.1042/BJ20041324

Toth, Marta; Osenkowski, Pamela; Hesek, Dusan; Brown, Stephen; Meroueh, Samy; Sakr, Wael; Mobashery, Shahriar; Fridman, Rafael

发表日期：2005

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