日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Activities of the Novel Bacterial Topoisomerase Inhibitor OSUAB-0284 against the Biothreat Pathogen Bacillus anthracis and Its Type II Topoisomerases

新型细菌拓扑异构酶抑制剂OSUAB-0284对生物威胁病原体炭疽杆菌及其II型拓扑异构酶的活性

Mann, Chelsea A; Halasohoris, Stephanie A; Gray, Annette M; Chua, Jennifer; Spencer, Jade L; Curry, Bobby J; Babyak, Ashley L; Klimko, Christopher P; Cote, Christopher K; West, Jason S; Mitton-Fry, Mark J; Meinig, J Matthew; Osheroff, Neil

Gyrase and Topoisomerase IV as Antibacterial Targets for Gepotidacin and Zoliflodacin: Teaching Old Enzymes New Tricks

吉泊他辛和佐利氟达辛的抗菌靶点:DNA促旋酶和拓扑异构酶IV:赋予老酶新技能

Osheroff, Neil

Anti-Mycobacterial Activity of Bacterial Topoisomerase Inhibitors with Dioxygenated Linkers

含双氧连接子的细菌拓扑异构酶抑制剂的抗分枝杆菌活性

Mitton-Fry, Mark J; Cummings, Jason E; Lu, Yanran; Armenia, Jillian F; Byl, Jo Ann W; Oviatt, Alexandria A; Bauman, Allison A; Robertson, Gregory T; Osheroff, Neil; Slayden, Richard A

Tips and Best Practices in Medical Education: Integrating Foundational and Clinical Sciences across the Medical Curriculum

医学教育技巧与最佳实践:将基础科学与临床科学融入医学课程

Osheroff, Neil

DNA Cleavage Mediated by Bacterial Type II Topoisomerases

细菌II型拓扑异构酶介导的DNA切割

Mann, Chelsea A; Osheroff, Neil

Bacterial type II topoisomerases cleave DNA in a species-specific manner

细菌II型拓扑异构酶以物种特异性方式切割DNA。

Morgan, Ian L; Jian, Jeffrey Y; Osheroff, Neil; Neuman, Keir C

DNA Supercoiling Catalyzed by Bacterial Gyrase

细菌DNA旋转酶催化的DNA超螺旋

Joshi, Samika; Osheroff, Neil

DNA Decatenation Catalyzed by Bacterial Topoisomerase IV

细菌拓扑异构酶IV催化的DNA解链

Armenia, Jillian F; Osheroff, Neil

Mechanism of Action of Gepotidacin: Well-Balanced Dual-Targeting against Neisseria gonorrhoeae Gyrase and Topoisomerase IV in Cells and In Vitro

吉泊他辛的作用机制:在细胞和体外对淋病奈瑟菌的DNA促旋酶和拓扑异构酶IV进行平衡的双重靶向抑制

Oviatt, Alexandria A; Collins, Jessica A; Mann, Chelsea A; Huang, Jianzhong; Mattern, Karen; Chan, Pan F; Osheroff, Neil

Interactions between Gepotidacin and Escherichia coli Gyrase and Topoisomerase IV: Genetic and Biochemical Evidence for Well-Balanced Dual-Targeting

吉泊汀与大肠杆菌促旋酶和拓扑异构酶 IV 之间的相互作用:平衡双靶向的遗传和生化证据

Alexandria A Oviatt, Elizabeth G Gibson, Jianzhong Huang, Karen Mattern, Keir C Neuman, Pan F Chan, Neil Osheroff