日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Loss of Parkinson's susceptibility gene LRRK2 promotes carcinogen-induced lung tumorigenesis

帕金森病易感基因LRRK2的缺失促进致癌物诱发的肺肿瘤发生

Chandra Lebovitz, Nicole Wretham, Maryam Osooly, Katy Milne, Tia Dash, Shelby Thornton, Basile Tessier-Cloutier, Paalini Sathiyaseelan, Svetlana Bortnik, Nancy Erro Go, Elizabeth Halvorsen, Rachel A Cederberg, Norman Chow, Nancy Dos Santos, Kevin L Bennewith, Brad H Nelson, Marcel B Bally, Wan L Lam

Irinophore C™, a lipid nanoparticle formulation of irinotecan, abrogates the gastrointestinal effects of irinotecan in a rat model of clinical toxicities

Irinophore C™ 是一种伊立替康脂质纳米颗粒制剂,可在临床毒性大鼠模型中消除伊立替康的胃肠道副作用。

Waterhouse, Dawn N; Sutherland, Brent W; Santos, Nancy Dos; Masin, Dana; Osooly, Maryam; Strutt, Dita; Ostlund, Christina; Anantha, Malathi; Harasym, Natashia; Manisali, Irina; Wehbe, Mohamed; Bally, Marcel B; Webb, Murray S

Validating the use of a luciferase labeled breast cancer cell line, MDA435LCC6, as a means to monitor tumor progression and to assess the therapeutic activity of an established anticancer drug, docetaxel (Dt) alone or in combination with the ILK inhibitor, QLT0267

验证使用荧光素酶标记的乳腺癌细胞系 MDA435LCC6 作为监测肿瘤进展和评估已上市抗癌药物多西他赛 (Dt) 单独使用或与 ILK 抑制剂 QLT0267 联合使用时的治疗活性的方法

Kalra, Jessica; Anantha, Malathi; Warburton, Corinna; Waterhouse, Dawn; Yan, Hong; Yang, Young-Joo; Strut, Dita; Osooly, Maryam; Masin, Dana; Bally, Marcel B