日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

A local solution to local load: Myo1E as a tension-responsive actuator in clathrin-mediated endocytosis

局部负荷的局部解决方案:Myo1E 作为网格蛋白介导的内吞作用中的张力响应致动器

Xu, Mengqi; Ostap, E Michael

Non-muscle tropomyosins inhibit myosin-19 and dynamically localize to mitochondrially associated actin filaments

非肌肉原肌球蛋白抑制肌球蛋白-19,并动态定位于线粒体相关的肌动蛋白丝上。

Thompson, Cameron P; Pollard, Luther W; Xu, Mengqi; Holzbaur, Erika L F; Ostap, E Michael

High-resolution structures of Myosin-IC reveal a unique actin-binding orientation, ADP release pathway, and power stroke trajectory

肌球蛋白-IC的高分辨率结构揭示了其独特的肌动蛋白结合方向、ADP释放途径和动力冲程轨迹。

Chavali, Sai Shashank; Carman, Peter J; Shuman, Henry; Ostap, E Michael; Sindelar, Charles V

A myosin hypertrophic cardiomyopathy mutation disrupts the super-relaxed state and boosts contractility by enhanced actin attachment

肌球蛋白肥厚型心肌病突变会破坏超松弛状态,并通过增强肌动蛋白附着来提高收缩力。

Cail, Robert C; Barua, Bipasha; Báez-Cruz, Faviolla A; Winkelmann, Donald A; Goldman, Yale E; Ostap, E Michael

S2Tag, a novel affinity tag for the capture and immobilization of coiled-coil proteins: Application to the study of human β-cardiac myosin

S2Tag,一种用于捕获和固定卷曲螺旋蛋白的新型亲和标签:在人β-心肌肌球蛋白研究中的应用

Barua, Bipasha; Cail, Robert C; Goldman, Yale E; Ostap, E Michael; Winkelmann, Donald A

Dynamics of β-cardiac myosin between the super-relaxed and disordered-relaxed states.

β-心肌肌球蛋白在超松弛状态和无序松弛状态之间的动力学

Cail Robert C, Báez-Cruz Faviolla A, Winkelmann Donald A, Goldman Yale E, Ostap E Michael

High resolution structures of Myosin-IC reveal a unique actin-binding orientation, ADP release pathway, and power stroke trajectory

肌球蛋白-IC的高分辨率结构揭示了其独特的肌动蛋白结合方向、ADP释放途径和动力冲程轨迹。

Chavali, Sai Shashank; Carman, Peter J; Shuman, Henry; Ostap, E Michael; Sindelar, Charles V

Myosin-1C differentially displaces tropomyosin isoforms altering their inhibition of motility

肌球蛋白-1C 差异性地取代原肌球蛋白亚型,从而改变它们对运动的抑制作用

Pollard, Luther W; Boczkowska, Malgorzata; Dominguez, Roberto; Ostap, E Michael

KIF1A is kinetically tuned to be a superengaging motor under hindering loads

KIF1A 经过动力学优化,即使在阻力负载下也能保持超强的啮合能力。

Pyrpassopoulos, Serapion; Gicking, Allison M; Zaniewski, Taylor M; Hancock, William O; Ostap, E Michael

Myosin modulators: emerging approaches for the treatment of cardiomyopathies and heart failure

肌球蛋白调节剂:治疗心肌病和心力衰竭的新兴方法

Day, Sharlene M; Tardiff, Jil C; Ostap, E Michael