日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Dynamic competition for hexon binding between core protein VII and lytic protein VI promotes adenovirus maturation and entry

核心蛋白VII和裂解蛋白VI之间对六邻体结合位点的动态竞争促进腺病毒的成熟和入侵。

Hernando-Pérez, Mercedes; Martín-González, Natalia; Pérez-Illana, Marta; Suomalainen, Maarit; Condezo, Gabriela N; Ostapchuk, Philomena; Gallardo, José; Menéndez, Margarita; Greber, Urs F; Hearing, Patrick; de Pablo, Pedro J; San Martín, Carmen

Adenovirus major core protein condenses DNA in clusters and bundles, modulating genome release and capsid internal pressure

腺病毒主要核心蛋白将DNA浓缩成簇和束状结构,从而调节基因组释放和衣壳内部压力。

Martín-González, Natalia; Hernando-Pérez, Mercedes; Condezo, Gabriela N; Pérez-Illana, Marta; Šiber, Antonio; Reguera, David; Ostapchuk, Philomena; Hearing, Patrick; San Martín, Carmen; de Pablo, Pedro J

Unnatural amino acid incorporation onto adenoviral (Ad) coat proteins facilitates chemoselective modification and retargeting of Ad type 5 vectors

将非天然氨基酸掺入腺病毒(Ad)外壳蛋白中,可以促进Ad 5型载体的化学选择性修饰和重定向。

Banerjee, Partha Sarathi; Ostapchuk, Philomena; Hearing, Patrick; Carrico, Isaac Sheridan

Characterization of Empty adenovirus particles assembled in the absence of a functional adenovirus IVa2 protein

对在缺乏功能性腺病毒IVa2蛋白的情况下组装的空腺病毒颗粒进行表征

Ostapchuk, Philomena; Almond, Matthew; Hearing, Patrick

Altering the Ad5 packaging domain affects the maturation of the Ad particles.

改变 Ad5 包装域会影响 Ad 颗粒的成熟

Alba Raul, Cots Dan, Ostapchuk Philomena, Bosch Assumpcio, Hearing Patrick, Chillon Miguel

Chemoselective attachment of small molecule effector functionality to human adenoviruses facilitates gene delivery to cancer cells

将小分子效应功能基团化学选择性地连接到人腺病毒上,可促进基因递送至癌细胞。

Banerjee, Partha Sarathi; Ostapchuk, Philomena; Hearing, Patrick; Carrico, Isaac

Minimal cis-acting elements required for adenovirus genome packaging

腺病毒基因组包装所需的最小顺式作用元件

Ostapchuk, Philomena; Hearing, Patrick