日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Development and Initial Characterization of Pigs with DNAI1 Mutations and Primary Ciliary Dyskinesia

DNAI1突变和原发性纤毛运动障碍猪的发育和初步表征

Abou Alaiwa, Mahmoud A; Hilkin, Brie M; Price, Margaret P; Gansemer, Nicholas D; Rector, Michael R; Stroik, Mal R; Powers, Linda S; Whitworth, Kristin M; Samuel, Melissa S; Jain, Akansha; Ostedgaard, Lynda S; Ernst, Sarah E; Philibert, Winter; Boyken, Linda D; Moninger, Thomas O; Karp, Phillip H; Hornick, Douglas B; Sinn, Patrick L; Fischer, Anthony J; Pezzulo, Alejandro A; McCray, Paul B Jr; Meyerholz, David K; Zabner, Joseph; Prather, Randy S; Welsh, Michael J; Stoltz, David A

Mucus aberrant properties in CF: Insights from cells and animal models

囊性纤维化患者黏液异常特性:来自细胞和动物模型的启示

Ehre, Camille; Hansson, Gunnar C; Thornton, David J; Ostedgaard, Lynda S

Lack of airway submucosal glands impairs respiratory host defenses

缺乏气道黏膜下腺会削弱呼吸道宿主的防御能力

Lynda S Ostedgaard, Margaret P Price, Kristin M Whitworth, Mahmoud H Abou Alaiwa, Anthony J Fischer, Akshaya Warrier, Melissa Samuel, Lee D Spate, Patrick D Allen, Brieanna M Hilkin, Guillermo S Romano Ibarra, Miguel E Ortiz Bezara, Brian J Goodell, Steven E Mather, Linda S Powers, Mallory R Stroik,

Early pathogenesis of cystic fibrosis gallbladder disease in a porcine model

猪模型中囊性纤维化胆囊疾病的早期发病机制

Zarei, Keyan; Stroik, Mallory R; Gansemer, Nick D; Thurman, Andrew L; Ostedgaard, Lynda S; Ernst, Sarah E; Thornell, Ian M; Powers, Linda S; Pezzulo, Alejandro A; Meyerholz, David K; Stoltz, David A

Mucus strands from submucosal glands initiate mucociliary transport of large particles

来自黏膜下腺体的黏液丝启动大颗粒的黏液纤毛清除。

Fischer, Anthony J; Pino-Argumedo, Maria I; Hilkin, Brieanna M; Shanrock, Cullen R; Gansemer, Nicholas D; Chaly, Anna L; Zarei, Keyan; Allen, Patrick D; Ostedgaard, Lynda S; Hoffman, Eric A; Stoltz, David A; Welsh, Michael J; Alaiwa, Mahmoud H Abou

Widespread airway distribution and short-term phenotypic correction of cystic fibrosis pigs following aerosol delivery of piggyBac/adenovirus

气溶胶输送 piggyBac/腺病毒后,囊性纤维化猪的气道分布广泛,短期表型纠正

Ashley L Cooney, Brajesh K Singh, Laura Marquez Loza, Ian M Thornell, Camilla E Hippee, Linda S Powers, Lynda S Ostedgaard, David K Meyerholz, Chris Wohlford-Lenane, David A Stoltz, Paul B McCray Jr, Patrick L Sinn

Motile cilia of human airway epithelia contain hedgehog signaling components that mediate noncanonical hedgehog signaling

人类呼吸道上皮细胞的运动纤毛含有 Hedgehog 信号通路成分,可介导非经典 Hedgehog 信号通路。

Mao, Suifang; Shah, Alok S; Moninger, Thomas O; Ostedgaard, Lynda S; Lu, Lin; Tang, Xiao Xiao; Thornell, Ian M; Reznikov, Leah R; Ernst, Sarah E; Karp, Philip H; Tan, Ping; Keshavjee, Shaf; Abou Alaiwa, Mahmoud H; Welsh, Michael J

Mucociliary Transport in Healthy and Cystic Fibrosis Pig Airways

健康猪和囊性纤维化猪气道中的黏液纤毛清除功能

Xie, Yuliang; Ostedgaard, Lynda; Abou Alaiwa, Mahmoud H; Lu, Lin; Fischer, Anthony J; Stoltz, David A

Gel-forming mucins form distinct morphologic structures in airways.

凝胶形成性粘蛋白在气道中形成独特的形态结构

Ostedgaard Lynda S, Moninger Thomas O, McMenimen James D, Sawin Nicholas M, Parker Connor P, Thornell Ian M, Powers Linda S, Gansemer Nicholas D, Bouzek Drake C, Cook Daniel P, Meyerholz David K, Abou Alaiwa Mahmoud H, Stoltz David A, Welsh Michael J

Alteration of protein function by a silent polymorphism linked to tRNA abundance

tRNA丰度相关的沉默多态性导致蛋白质功能改变

Sebastian Kirchner,Zhiwei Cai,Robert Rauscher,Nicolai Kastelic,Melanie Anding,Andreas Czech,Bertrand Kleizen,Lynda S Ostedgaard,Ineke Braakman,David N Sheppard,Zoya Ignatova