Population Pharmacokinetic Modeling of Total and Free Ceftriaxone in Critically Ill Children and Young Adults and Monte Carlo Simulations Support Twice Daily Dosing for Target Attainment
对危重儿童和青少年患者头孢曲松总浓度和游离浓度的群体药代动力学模型以及蒙特卡罗模拟结果支持每日两次给药以达到目标浓度。
期刊:Antimicrobial Agents and Chemotherapy
影响因子:4.5
doi:10.1128/AAC.01427-21
Tang Girdwood, Sonya; Dong, Min; Tang, Peter; Stoneman, Erin; Jones, Rhonda; Yunger, Toni; Ostermeier, Austin; Curry, Calise; Forton, Melissa; Hail, Traci; Mullaney, Randi; Lahni, Patrick; Punt, Nieko; Kaplan, Jennifer; Vinks, Alexander A