日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Divergent Effects of Dnmt3a and Tet2 Mutations on Hematopoietic Progenitor Cell Fitness.

Dnmt3a 和 Tet2 突变对造血祖细胞适应性的不同影响

Ostrander Elizabeth L, Kramer Ashley C, Mallaney Cates, Celik Hamza, Koh Won Kyun, Fairchild Jake, Haussler Emily, Zhang Christine R C, Challen Grant A

Enforced differentiation of Dnmt3a-null bone marrow leads to failure with c-Kit mutations driving leukemic transformation

强制分化Dnmt3a缺失的骨髓会导致c-Kit突变驱动白血病转化,最终导致分化失败。

Celik, Hamza; Mallaney, Cates; Kothari, Alok; Ostrander, Elizabeth L; Eultgen, Elizabeth; Martens, Andrew; Miller, Christopher A; Hundal, Jasreet; Klco, Jeffery M; Challen, Grant A