日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Troxipide nanosuspensions prevent indomethacin‑induced gastrointestinal lesions in adjuvant-induced arthritis rats

曲唑吡坦纳米混悬液可预防佐剂诱导关节炎大鼠中吲哚美辛引起的胃肠道损伤

期刊:Journal of Pharmaceutical Health Care and Sciences
影响因子:1.2
doi:10.1186/s40780-026-00542-w
Fujimoto, Kazuya; Otake, Hiroko; Tanaka, Rie; Ogata, Fumihiko; Fujii, Chika; Yamamoto, Naoki; Kawasaki, Naohito; Ishizaka, Toshihiko; Kotake, Takeshi; Nagai, Noriaki
关节炎
Rat
发表日期：2026
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Solid Tranilast Nanocrystal-Loaded Cationic Contact Lenses for Sustained Ocular Drug Delivery

用于持续眼部药物递送的固体曲尼司特纳米晶体负载阳离子隐形眼镜

期刊:Pharmaceutics
影响因子:5.5
doi:10.3390/pharmaceutics17101240
Kobayakawa, Shinichiro; Matsunaga, Toru; Otake, Hiroko; Hino, Shiori; Ogata, Fumihiko; Misra, Manju; Kanai, Kazutaka; Kawasaki, Naohito; Nagai, Noriaki
发表日期：2025
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Design of Tranilast-Loaded Cation-Type Contact Lens for Sustainable Ocular Drug Delivery

载有曲尼司特的阳离子型隐形眼镜的设计及其在眼部药物可持续递送中的应用

期刊:Pharmaceutics
影响因子:5.5
doi:10.3390/pharmaceutics17060712
Matsunaga, Toru; Kuwamura, Ryotaro; Hino, Shiori; Ogata, Fumihiko; Otake, Hiroko; Kawasaki, Naohito; Kobayakawa, Shinichiro; Nagai, Noriaki
发表日期：2025
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Dermal Formulation Incorporating Isoconazole Nitrate Nanoparticles Offers High Absorption into Skin and Antimicrobial Effect Against Candida albicans

含有硝酸异康唑纳米颗粒的皮肤制剂具有高皮肤吸收率和抗白色念珠菌的抗菌效果。

期刊:Pharmaceutics
影响因子:5.5
doi:10.3390/pharmaceutics17121519
Harada, Ayako; Tanaka, Rie; Otake, Hiroko; Yoshimura, Masanori; Wada, Tae; Nagahama, Tohru; Nagai, Noriaki
发表日期：2025
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Pharmacological Behavior of Propylene Glycol/Polyvinyl Alcohol Hydrogel Incorporating Indomethacin Nanocrystals in the Skin

丙二醇/聚乙烯醇水凝胶负载吲哚美辛纳米晶体在皮肤中的药理学行为

期刊:Gels
影响因子:5.3
doi:10.3390/gels11040251
Otake, Hiroko; Ogata, Fumihiko; Nakazawa, Yosuke; Misra, Manju; Tsubaki, Masanobu; Kawasaki, Naohito; Nagai, Noriaki
发表日期：2025
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Semiquantitative analysis of protein expression in heated rat lens using shotgun proteomics

利用鸟枪法蛋白质组学对加热大鼠晶状体中的蛋白质表达进行半定量分析

期刊:Molecular Medicine Reports
影响因子:3.5
doi:10.3892/mmr.2024.13391
Otake, Hiroko; Masuda, Shuya; Yamamoto, Tetsushi; Miyata, Yoshiki; Nakazawa, Yosuke; Yamamoto, Naoki; Taga, Atsushi; Sasaki, Hiroshi; Nagai, Noriaki
Rat
发表日期：2025
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Dermal formulation based on carbopol and Gum Arabic improves skin retention of indomethacin

基于卡波姆和阿拉伯胶的皮肤制剂可提高吲哚美辛在皮肤中的保留率。

期刊:PLoS One
影响因子:2.6
doi:10.1371/journal.pone.0326051
Otake, Hiroko; Fumihiko, Ogata; Nakazawa, Yosuke; Misra, Manju; Tsubaki, Masanobu; Kawasaki, Naohito; Nagai, Noriaki
发表日期：2025
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Changes in Protein Expression in Warmed Human Lens Epithelium Cells Using Shotgun Proteomics

利用鸟枪法蛋白质组学研究温热条件下人晶状体上皮细胞中蛋白质表达的变化

期刊:Medicina-Lithuania
影响因子:2.4
doi:10.3390/medicina61020286
Otake, Hiroko; Yamamoto, Tetsushi; Yamamoto, Naoki; Nakazawa, Yosuke; Miyata, Yoshiki; Taga, Atsushi; Sasaki, Hiroshi; Nagai, Noriaki
上皮细胞
细胞生物学
Human
发表日期：2025
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Clinical Utility of Targeted Next-Generation Sequencing for Determining Human Epidermal Growth Factor Receptor 2 Status and Optimizing Targeted Therapy in Breast Cancer

靶向二代测序在确定人表皮生长因子受体2状态和优化乳腺癌靶向治疗中的临床应用

期刊:World Journal of Oncology
影响因子:2.2
doi:10.14740/wjon2583
Hara, Yoshimi; Moro, Kazuki; Ichikawa, Hiroshi; Tsuchida, Junko; Uchida, Haruka; Naruse, Kana; Otake, Hiroko; Obata, Yasuo; Sugai, Mika; Shimada, Yoshifumi; Sakata, Jun; Umezu, Hajime; Koyama, Yu; Okuda, Shujiro; Takabe, Kazuaki; Wakai, Toshifumi
肿瘤
肿瘤免疫
信号转导
乳腺癌
Human
发表日期：2025
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Copolymerized Polymers Based on Cyclodextrins and Cationic Groups Enhance Therapeutic Effect of Rebamipide in the N-Acetylcysteine-Treated Dry Eye Model

基于环糊精和阳离子基团的共聚聚合物可增强瑞巴派特在N-乙酰半胱氨酸治疗的干眼模型中的治疗效果

期刊:Drug Design Development and Therapy
影响因子:5.1
doi:10.2147/DDDT.S469445
Otake, Hiroko; Kobayashi, Ko; Kadowaki, Reita; Kosaka, Taiyo; Itahashi, Mizuki; Tsubaki, Masanobu; Matsuda, Masaru; Iwakiri, Norio; Harata, Eiji; Nagai, Noriaki
发表日期：2024
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