Dual ENPP1/ATM depletion blunts DNA damage repair boosting radioimmune efficacy to abrogate triple-negative breast cancer
ENPP1/ATM双重缺失会削弱DNA损伤修复，从而增强放射免疫疗法对三阴性乳腺癌的疗效。
期刊:Signal Transduction and Targeted Therapy
影响因子:52.7
doi:10.1038/s41392-025-02271-2
Ruiz-Fernández de Córdoba, Borja; Valencia, Karmele; Welch, Connor; Moreno, Haritz; Martínez-Canarias, Susana; Zandueta, Carolina; Gómez, Eduardo; Calvo, Alfonso; Otegui, Nerea; Echepare, Mirari; Garzón, Ignacio; Ajona, Daniel; Lara-Astiaso, David; Guruceaga, Elisabeth; Guembe, Laura; Pío, Rubén; Melero, Ignacio; Vicent, Silve; Pastor, Fernando; Martínez-Monge, Rafael; Lecanda, Fernando
ENPP1
毒理研究
免疫/内分泌
ATM
乳腺癌
肿瘤
肿瘤免疫
