A long-lasting PI3Kδ inhibitor zandelisib forms a water-shielded hydrogen bond with p110δ and demonstrates sustained inhibitory effects.
长效 PI3Kδ 抑制剂 zandelisib 与 p110δ 形成水屏蔽氢键，并表现出持续的抑制作用
期刊:American Journal of Cancer Research
影响因子:2.9
doi:10.62347/JCGQ1004
Kunieda Kana, Nagiri Chisae, Watanabe Miwa, Yoshida Tadashi, Zou Jian, Kaneda Ayumi, Takahashi Yuichi, Aburai Kenichi, Saito Jun-Ichi, Umehara Hiroshi, Otsu Yoshiaki, Ishii Toshihiko
