日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Mammalian polycomb-like Pcl2/Mtf2 is a novel regulatory component of PRC2 that can differentially modulate polycomb activity both at the Hox gene cluster and at Cdkn2a genes.

哺乳动物多梳蛋白样 Pcl2/Mtf2 是 PRC2 的一种新型调控成分,可以差异性地调节 Hox 基因簇和 Cdkn2a 基因的多梳蛋白活性

Li Xiangzhi, Isono Kyo-Ichi, Yamada Daisuke, Endo Takaho A, Endoh Mitsuhiro, Shinga Jun, Mizutani-Koseki Yoko, Otte Arie P, Casanova Miguel, Kitamura Hiroshi, Kamijo Takehiko, Sharif Jafar, Ohara Osamu, Toyada Tetsuro, Bernstein Bradley E, Brockdorff Neil, Koseki Haruhiko

The use of a stringent selection system allows the identification of DNA elements that augment gene expression.

严格的筛选系统能够识别增强基因表达的DNA元件

Hoeksema Femke, van Blokland Rik, Siep Michel, Hamer Karien, Siersma Tjalling, den Blaauwen Jan, Verhees John, Otte Arie P

Expression of the polycomb-group gene BMI1 is related to an unfavourable prognosis in primary nodal DLBCL

多梳蛋白基因BMI1的表达与原发性淋巴结弥漫性大B细胞淋巴瘤(DLBCL)的不良预后相关。

van Galen, Joost C; Muris, Jettie J F; Oudejans, Joost J; Vos, Wim; Giroth, Cindy P E; Ossenkoppele, Gert J; Otte, Arie P; Raaphorst, Frank M; Meijer, Chris J L M

Increased expression of the EZH2 polycomb group gene in BMI-1-positive neoplastic cells during bronchial carcinogenesis

支气管癌发生过程中,BMI-1阳性肿瘤细胞中EZH2多梳蛋白基因表达增加

Breuer, Roderick H J; Snijders, Peter J F; Smit, Egbert F; Sutedja, Thomas G; Sewalt, Richard G A B; Otte, Arie P; van Kemenade, Folkert J; Postmus, Pieter E; Meijer, Chris J L M; Raaphorst, Frank M

Poorly differentiated breast carcinoma is associated with increased expression of the human polycomb group EZH2 gene

低分化乳腺癌与人多梳蛋白组 EZH2 基因表达增加有关。

Raaphorst, Frank M; Meijer, Chris J L M; Fieret, Elly; Blokzijl, Tjasso; Mommers, Ellen; Buerger, Horst; Packeisen, Jens; Sewalt, Richard A B; Otte, Arie P; van Diest, Paul J