日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

FAM20B Gain-of-Function Blocks the Synthesis of Glycosaminoglycan Chains of Proteoglycans and Inhibits Proliferation and Migration of Glioblastoma Cells

FAM20B 功能获得性突变阻断蛋白聚糖糖胺聚糖链的合成,并抑制胶质母细胞瘤细胞的增殖和迁移。

Lydia Barré ,Irfan Shaukat ,Mohamed Ouzzine

Xylosyltransferase I mediates the synthesis of proteoglycans with long glycosaminoglycan chains and controls chondrocyte hypertrophy and collagen fibers organization of in the growth plate

木糖基转移酶 I 介导具有长糖胺聚糖链的蛋白聚糖的合成,并控制生长板中的软骨细胞肥大和胶原纤维组织

Mahdia Taieb #, Dima Ghannoum #, Lydia Barré, Mohamed Ouzzine

Differential Effects of D-Galactose Supplementation on Golgi Glycosylation Defects in TMEM165 Deficiency

D-半乳糖补充剂对TMEM165缺乏症中高尔基体糖基化缺陷的不同影响

Durin, Zoé; Houdou, Marine; Morelle, Willy; Barré, Lydia; Layotte, Aurore; Legrand, Dominique; Ouzzine, Mohamed; Foulquier, François

TMEM165 a new player in proteoglycan synthesis: loss of TMEM165 impairs elongation of chondroitin- and heparan-sulfate glycosaminoglycan chains of proteoglycans and triggers early chondrocyte differentiation and hypertrophy

TMEM165 是蛋白聚糖合成中的新角色:TMEM165 的缺失会损害蛋白聚糖中硫酸软骨素和硫酸乙酰肝素糖胺聚糖链的延伸,并引发早期软骨细胞分化和肥大。

Sajida Khan ,Malak Sbeity ,François Foulquier ,Lydia Barré ,Mohamed Ouzzine

Non-canonical Wnt induces chondrocyte de-differentiation through Frizzled 6 and DVL-2/B-raf/CaMKIIα/syndecan 4 axis

非经典Wnt信号通路通过Frizzled 6和DVL-2/B-raf/CaMKIIα/syndecan 4轴诱导软骨细胞去分化。

Xie, Zhe; Khair, Mostafa; Shaukat, Irfan; Netter, Patrick; Mainard, Didier; Barré, Lydia; Ouzzine, Mohamed

Targeting of Proteoglycan Synthesis Pathway: A New Strategy to Counteract Excessive Matrix Proteoglycan Deposition and Transforming Growth Factor-β1-Induced Fibrotic Phenotype in Lung Fibroblasts

靶向蛋白多糖合成途径:对抗肺成纤维细胞中过多基质蛋白多糖沉积和转化生长因子-β1诱导的纤维化表型的新策略

Irfan Shaukat, Lydia Barré, Narayanan Venkatesan, Dong Li, Jean-Claude Jaquinet, Sylvie Fournel-Gigleux, Mohamed Ouzzine

Probing the acceptor active site organization of the human recombinant β1,4-galactosyltransferase 7 and design of xyloside-based inhibitors

探索人类重组β1,4-半乳糖基转移酶7受体活性位点的组织和木糖苷类抑制剂的设计

Mineem Saliba, Nick Ramalanjaona, Sandrine Gulberti, Isabelle Bertin-Jung, Aline Thomas, Samir Dahbi, Chrystel Lopin-Bon, Jean-Claude Jacquinet, Christelle Breton, Mohamed Ouzzine, Sylvie Fournel-Gigleux

The UDP-glucuronosyltransferases of the blood-brain barrier: their role in drug metabolism and detoxication

血脑屏障的UDP-葡萄糖醛酸转移酶:它们在药物代谢和解毒中的作用

Ouzzine, Mohamed; Gulberti, Sandrine; Ramalanjaona, Nick; Magdalou, Jacques; Fournel-Gigleux, Sylvie

Xylosyltransferase-I regulates glycosaminoglycan synthesis during the pathogenic process of human osteoarthritis

木糖基转移酶-I在人类骨关节炎的发病过程中调节糖胺聚糖的合成

Venkatesan, Narayanan; Barré, Lydia; Bourhim, Mustapha; Magdalou, Jacques; Mainard, Didier; Netter, Patrick; Fournel-Gigleux, Sylvie; Ouzzine, Mohamed

Modifications of the glycosaminoglycan-linkage region of proteoglycans: phosphorylation and sulfation determine the activity of the human beta1,4-galactosyltransferase 7 and beta1,3-glucuronosyltransferase I

蛋白聚糖糖胺聚糖连接区的修饰:磷酸化和硫酸化决定了人β1,4-半乳糖基转移酶7和β1,3-葡萄糖醛酸基转移酶I的活性

Gulberti, Sandrine; Lattard, Virginie; Fondeur, Magali; Jacquinet, Jean-Claude; Mulliert, Guillermo; Netter, Patrick; Magdalou, Jacques; Ouzzine, Mohamed; Fournel-Gigleux, Sylvie