日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Sucralose Consumption Ablates Cancer Immunotherapy Response through Microbiome Disruption

三氯蔗糖的摄入通过破坏微生物群来消除癌症免疫疗法反应

Kristin M Morder # ,Madison Nguyen # ,Drew N Wilfahrt # ,Zakaria Larbi Dahmani ,Ansen B P Burr ,Bingxian Xie ,Michael Morikone ,Hector Nieves-Rosado ,William G Gunn ,Drew E Hurd ,Hong Wang ,Steven J Mullett ,Kaitlin Bossong ,Stacy L Gelhaus ,Dhivyaa Rajasundaram ,Lawrence P Kane ,Greg M Delgoffe ,Jishnu Das ,Diwakar Davar ,Abigail E Overacre-Delgoffe

Mouse innate resistance to Neospora caninum infection is driven by early production of IFNγ by NK cells in response to parasite ligands

小鼠对犬新孢子虫感染的先天性抵抗力是由NK细胞在寄生虫配体刺激下早期产生IFNγ驱动的。

Coombs, R S; Overacre-Delgoffe, A E; Bhattacharjee, A; Hand, T W; Boyle, J P

Leveraging immune resistance archetypes in solid cancer to inform next-generation anticancer therapies

利用实体瘤中的免疫抵抗原型来指导下一代抗癌疗法

Anderson, Kristin G; Braun, David A; Buqué, Aitziber; Gitto, Sarah B; Guerriero, Jennifer L; Horton, Brendan; Keenan, Bridget P; Kim, Teresa S; Overacre-Delgoffe, Abigail; Ruella, Marco; Triplett, Todd A; Veeranki, Omkara; Verma, Vivek; Zhang, Fan

Excess Dietary Sugar Alters Colonocyte Metabolism and Impairs the Proliferative Response to Damage

膳食中过量的糖分会改变结肠细胞代谢,并损害其对损伤的增殖反应。

Ansen H P Burr ,Junyi Ji ,Kadir Ozler ,Heather L Mentrup ,Onur Eskiocak ,Brian Yueh ,Rachel Cumberland ,Ashley V Menk ,Natalie Rittenhouse ,Chris W Marshall ,Pailin Chiaranunt ,Xiaoyi Zhang ,Lauren Mullinax ,Abigail Overacre-Delgoffe ,Vaughn S Cooper ,Amanda C Poholek ,Greg M Delgoffe ,Kevin P Mollen ,Semir Beyaz ,Timothy W Hand

Regulation of tissue-resident memory T cells by the Microbiota

微生物群对组织驻留记忆T细胞的调控

Overacre-Delgoffe, Abigail E; Hand, Timothy W

Metabolic support of tumour-infiltrating regulatory T cells by lactic acid

乳酸对肿瘤浸润性调节性T细胞的代谢支持

McLane J Watson ,Paolo D A Vignali ,Steven J Mullett ,Abigail E Overacre-Delgoffe ,Ronal M Peralta ,Stephanie Grebinoski ,Ashley V Menk ,Natalie L Rittenhouse ,Kristin DePeaux ,Ryan D Whetstone ,Dario A A Vignali ,Timothy W Hand ,Amanda C Poholek ,Brett M Morrison ,Jeffrey D Rothstein ,Stacy G Wendell ,Greg M Delgoffe

Microbiota-specific T follicular helper cells drive tertiary lymphoid structures and anti-tumor immunity against colorectal cancer

微生物群特异性 T 滤泡辅助细胞驱动三级淋巴结构和针对结直肠癌的抗肿瘤免疫

Abigail E Overacre-Delgoffe, Hannah J Bumgarner, Anthony R Cillo, Ansen H P Burr, Justin T Tometich, Amrita Bhattacharjee, Tullia C Bruno, Dario A A Vignali, Timothy W Hand

Environmental enteric dysfunction induces regulatory T cells that inhibit local CD4+ T cell responses and impair oral vaccine efficacy

环境性肠道功能障碍会诱导调节性T细胞,从而抑制局部CD4+ T细胞反应并降低口服疫苗的效力。

Amrita Bhattacharjee ,Ansen H P Burr ,Abigail E Overacre-Delgoffe ,Justin T Tometich ,Deyi Yang ,Brydie R Huckestein ,Jonathan L Linehan ,Sean P Spencer ,Jason A Hall ,Oliver J Harrison ,Denise Morais da Fonseca ,Elizabeth B Norton ,Yasmine Belkaid ,Timothy W Hand

Prevalence of intratumoral regulatory T cells expressing neuropilin-1 is associated with poorer outcomes in patients with cancer

肿瘤内表达神经纤毛蛋白-1的调节性T细胞的普遍存在与癌症患者预后不良相关。

Christopher A Chuckran ,Anthony R Cillo ,Jessica Moskovitz ,Abigail Overacre-Delgoffe ,Ashwin S Somasundaram ,Feng Shan ,Grant C Magnon ,Sheryl R Kunning ,Irina Abecassis ,Amer H Zureikat ,James Luketich ,Arjun Pennathur ,John Sembrat ,Mauricio Rojas ,Daniel T Merrick ,Sarah E Taylor ,Brian Orr ,Francesmary Modugno ,Ron Buckanovich ,Robert E Schoen ,Seungwon Kim ,Umamaheswar Duvvuri ,Herbert Zeh ,Robert Edwards ,John M Kirkwood ,Lan Coffman ,Robert L Ferris ,Tullia C Bruno ,Dario A A Vignali

Considerations for treatment duration in responders to immune checkpoint inhibitors

对免疫检查点抑制剂有反应的患者,治疗持续时间需要考虑哪些因素

Marron, Thomas U; Ryan, Aideen E; Reddy, Sangeetha M; Kaczanowska, Sabina; Younis, Rania H; Thakkar, Dipti; Zhang, Jiajia; Bartkowiak, Todd; Howard, Rachel; Anderson, Kristin G; Olson, Daniel; Naqash, Abdul Rafeh; Patel, Ravi B; Sachdev, Esha; Rodriguez-Ruiz, Maria E; Sheffer, Michal; Church, Sarah; Fuhrman, Christopher; Overacre-Delgoffe, Abigail; Nguyen, Rosa; Florou, Vaia; Thaxton, Jessica E; Aggen, David H; Guerriero, Jennifer L