Cocaine-induced chromatin remodeling increases brain-derived neurotrophic factor transcription in the rat medial prefrontal cortex, which alters the reinforcing efficacy of cocaine.

可卡因诱导的染色质重塑增加了大鼠内侧前额叶皮层中脑源性神经营养因子的转录，从而改变了可卡因的强化效力