日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Activity-restoring mutations in the histamine H(3) receptor increase constitutive activity and reduce structural stability.

组胺 H(3) 受体的活性恢复突变会增加组成活性并降低结构稳定性。

期刊:Protein Science
影响因子:5.2
doi:10.1002/pro.70408
Nakajima Ami, Kaneko Hiroto, Oyama Kosuke, Kuchiji Misumi, Itakura Ayane, Arai Chiaki, Shiroishi Mitsunori
信号转导
发表日期：2026
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Hericenone C exhibits anti-nociceptive effects through RORα-mediated suppression of TLR4 transcription.

猴头菇酮 C 通过 RORα 介导的 TLR4 转录抑制发挥镇痛作用。

期刊:Frontiers in Pharmacology
影响因子:4.8
doi:10.3389/fphar.2026.1703176
Li Junhao, Hamamura Kengo, Yoshida Yuya, Kawano Shimpei, Uchinomiya Shohei, Xie Jiahongyi, Scuteri Damiana, Ruan Yang, Tanihara Tomohito, Fukuoka Kohei, Zaitsu Orion, Tsurusaki Fumiaki, Tsukamoto Ryotaro, Nishi Takumi, Fukuda Taiki, Hamasaki Tsukasa, Oyama Kosuke, Bagetta Giacinto, Ojida Akio, Shimizu Kuniyoshi, Zhang Chaofeng, Ohdo Shigehiro, Matsunaga Naoya
TLR4
发表日期：2026
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Liposome Encapsulation Enhances Ripasudil Therapeutic Efficacy Against Proliferative Vitreoretinal Diseases: Implications in Advanced Ocular Treatment.

脂质体包裹增强利帕舒地尔治疗增生性玻璃体视网膜疾病的疗效：对高级眼科治疗的意义

期刊:Investigative Ophthalmology & Visual Science
影响因子:4.7
doi:10.1167/iovs.66.6.56
Ji Rui, Ishikawa Keijiro, Tan Wei, Mori Kenichiro, Tsukamoto Ryotaro, Matsunaga Naoya, Kiyohara Kohei, Fukuda Yosuke, Wada Iori, Isobe Tomoyuki, Tanihara Tomohito, Yoshida Yuya, Mayanagi Kouta, Oyama Kosuke, Terada Yuma, Otsuki Kaita, Hamamura Kengo, Kikuchi Hiroshi, Nakao Shintaro, Yoshida Shigeo, Kannan Ram, Ohdo Shigehiro, Sonoda Koh-Hei
其它
发表日期：2025
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Microcurrent stimulation induces cell death in p53-mutant and 5-FU-resistant breast cancer.

微电流刺激可诱导 p53 突变型和 5-FU 耐药型乳腺癌细胞死亡

期刊:Journal of Biological Chemistry
影响因子:3.9
doi:10.1016/j.jbc.2025.110414
Tanihara Tomohito, Yoshida Yuya, Ogino Takashi, Terada Yuma, Tsurusaki Fumiaki, Hamasaki Keika, Otsuki Kaita, Fukuoka Kohei, Oyama Kosuke, Tsuruta Akito, Hamamura Kengo, Mayanagi Kouta, Koyanagi Satoru, Murakami Yuichi, Ono Mayumi, Kuwano Michihiko, Ohdo Shigehiro, Matsunaga Naoya
细胞生物学
乳腺癌
P53
肿瘤免疫
发表日期：2025
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Relationship between protein conformational stability and its immunogenicity when administering antigens to mice using adjuvants-Analysis employed the CH2 domain in human antibodies

利用佐剂向小鼠注射抗原时，蛋白质构象稳定性与其免疫原性之间的关系——分析采用了人抗体中的CH2结构域

期刊:PLoS One
影响因子:2.6
doi:10.1371/journal.pone.0307320
Oyama, Kosuke; Ueda, Tadashi
免疫/内分泌
发表日期：2024
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Enhancing thermal stability in the CH(2) domain to suppress aggregation through the introduction of simultaneous disulfide bonds in Pichia pastoris

通过在毕赤酵母中引入同时存在的二硫键来增强CH(2)结构域的热稳定性，从而抑制聚集

期刊:Protein Science
影响因子:5.2
doi:10.1002/pro.4831
Oyama, Kosuke; Nakakido, Makoto; Ohkuri, Takatoshi; Nakamura, Hitomi; Tsumoto, Kouhei; Ueda, Tadashi
发表日期：2023
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Allergic Bronchopulmonary Mycosis Complicated with Lung Adenocarcinoma

过敏性支气管肺真菌病并发肺腺癌

期刊:Internal Medicine
影响因子:1.1
doi:10.2169/internalmedicine.9437-22
Ohnishi, Hiroshi; Sakai Tsuji, Kimiko; Iguchi, Mitsuko; Oyama, Kosuke; Yokoyama, Akihito
微生物学
肿瘤
肿瘤免疫
发表日期：2022
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CENP-T-W-S-X forms a unique centromeric chromatin structure with a histone-like fold

CENP-TWSX 形成独特的着丝粒染色质结构，具有组蛋白样折叠

期刊:Cell
影响因子:45.5
doi:10.1016/j.cell.2011.11.061
Tatsuya Nishino, Kozo Takeuchi, Karen E Gascoigne, Aussie Suzuki, Tetsuya Hori, Takuji Oyama, Kosuke Morikawa, Iain M Cheeseman, Tatsuo Fukagawa
表观遗传
发表日期：2012
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