日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Differential regulation of MYC expression by PKHD1/Pkhd1 in human and mouse kidneys: phenotypic implications for recessive polycystic kidney disease

PKHD1/Pkhd1 在人类和小鼠肾脏中对 MYC 表达的差异调节:对隐性多囊肾病的表型影响

Naoe Harafuji #, Chaozhe Yang #, Maoqing Wu, Girija Thiruvengadam, Heather Gordish-Dressman, R Griffin Thompson, P Darwin Bell, Avi Z Rosenberg, Claudia Dafinger, Max C Liebau, Zsuzsanna Bebok, Ljubica Caldovic, Lisa M Guay-Woodford

Cystin is required for maintaining fibrocystin (FPC) levels and safeguarding proteome integrity in mouse renal epithelial cells: A mechanistic connection between the kidney defects in cpk mice and human ARPKD

胱氨酸是维持小鼠肾上皮细胞中纤维囊蛋白 (FPC) 水平和保护蛋白质组完整性所必需的:cpk 小鼠肾脏缺陷与人类 ARPKD 之间的机制联系

Yiming J Zhang, Chaozhe Yang, Wei Wang, Naoe Harafuji, Piotr Stasiak, P Darwin Bell, Ljubica Caldovic, Elizabeth Sztul, Lisa M Guay-Woodford, Zsuzsanna Bebok

An American Physiological Society cross-journal Call for Papers on "Deconstructing Organs: Single-Cell Analyses, Decellularized Organs, Organoids, and Organ-on-a-Chip Models"

美国生理学会跨期刊征稿,主题为“解构器官:单细胞分析、脱细胞器官、类器官和芯片器官模型”。

Adams, Josephine C; Bell, P Darwin; Bodine, Sue C; Brooks, Heddwen L; Bunnett, Nigel; Joe, Bina; Keehan, Kara Hansell; Kleyman, Thomas R; Marette, André; Morty, Rory E; Ramírez, Jan-Marino; Thomsen, Morten B; Yates, Bill J; Zucker, Irving H

Interferon Regulatory Factor-5 in Resident Macrophage Promotes Polycystic Kidney Disease

驻留巨噬细胞中的干扰素调节因子-5促进多囊肾病

Kurt A Zimmerman, Jifeng Huang, Lan He, Dustin Z Revell, Zhang Li, Jung-Shan Hsu, Wayne R Fitzgibbon, E Starr Hazard, Gary Hardiman, Michal Mrug, P Darwin Bell, Bradley K Yoder, Takamitsu Saigusa

Truncating PKHD1 and PKD2 mutations alter energy metabolism

PKHD1 和 PKD2 截断突变会改变能量代谢

Chumley, Phillip; Zhou, Juling; Mrug, Sylvie; Chacko, Balu; Parant, John M; Challa, Anil K; Wilson, Landon S; Berryhill, Taylor F; Barnes, Stephen; Kesterson, Robert A; Bell, P Darwin; Darley-Usmar, Victor M; Yoder, Bradley K; Mrug, Michal

Loss of primary cilia increases polycystin-2 and TRPV4 and the appearance of a nonselective cation channel in the mouse cortical collecting duct

小鼠皮质集合管中原发性纤毛的缺失会导致多囊蛋白-2和TRPV4的表达增加,并出现非选择性阳离子通道。

Saigusa, Takamitsu; Yue, Qiang; Bunni, Marlene A; Bell, P Darwin; Eaton, Douglas C

TRPV4 activation of endothelial nitric oxide synthase resists nonalcoholic fatty liver disease by blocking CYP2E1-mediated redox toxicity

TRPV4激活内皮型一氧化氮合酶,通过阻断CYP2E1介导的氧化还原毒性来抵抗非酒精性脂肪肝疾病。

Seth, Ratanesh K; Das, Suvarthi; Dattaroy, Diptadip; Chandrashekaran, Varun; Alhasson, Firas; Michelotti, Gregory; Nagarkatti, Mitzi; Nagarkatti, Prakash; Diehl, Anna Mae; Bell, P Darwin; Liedtke, Wolfgang; Chatterjee, Saurabh

Suppressing angiotensinogen synthesis attenuates kidney cyst formation in a Pkd1 mouse model

抑制血管紧张素原合成可减轻 Pkd1 小鼠模型中的肾囊肿形成

Saigusa, Takamitsu; Dang, Yujing; Mullick, Adam E; Yeh, Steve T; Zile, Michael R; Baicu, Catalin F; Bell, P Darwin

Centrobin-mediated regulation of the centrosomal protein 4.1-associated protein (CPAP) level limits centriole length during elongation stage

Centrobin 介导的着丝粒蛋白 4.1 相关蛋白 (CPAP) 水平调节限制了伸长阶段着丝粒的长度

Radhika Gudi, Courtney J Haycraft, P Darwin Bell, Zihai Li, Chenthamarakshan Vasu

Activation of the intrarenal renin-angiotensin-system in murine polycystic kidney disease

小鼠多囊肾病中肾内肾素-血管紧张素系统的激活

Takamitsu Saigusa, Yujing Dang, Marlene A Bunni, May Y Amria, Stacy L Steele, Wayne R Fitzgibbon, P Darwin Bell