日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

HPV16 E5 Mediates Resistance to PD-L1 Blockade and Can Be Targeted with Rimantadine in Head and Neck Cancer

HPV16 E5介导对PD-L1阻断的耐药性,可作为头颈癌治疗的靶点,使用金刚烷胺进行治疗。

Miyauchi, Sayuri; Sanders, P Dominick; Guram, Kripa; Kim, Sangwoo S; Paolini, Francesca; Venuti, Aldo; Cohen, Ezra E W; Gutkind, J Silvio; Califano, Joseph A; Sharabi, Andrew B

B Cells Improve Overall Survival in HPV-Associated Squamous Cell Carcinomas and Are Activated by Radiation and PD-1 Blockade

B细胞可提高HPV相关鳞状细胞癌患者的总体生存率,并可被放射线和PD-1阻断激活。

Kim, Sangwoo S; Shen, Sarek; Miyauchi, Sayuri; Sanders, P Dominick; Franiak-Pietryga, Ida; Mell, Loren; Gutkind, J Silvio; Cohen, Ezra E W; Califano, Joseph A; Sharabi, Andrew B

Macrophage Syk-PI3Kγ Inhibits Antitumor Immunity: SRX3207, a Novel Dual Syk-PI3K Inhibitory Chemotype Relieves Tumor Immunosuppression

巨噬细胞 Syk-PI3Kγ 抑制抗肿瘤免疫:新型双重 Syk-PI3K 抑制剂 SRX3207 可缓解肿瘤免疫抑制

Joshi, Shweta; Liu, Kevin X; Zulcic, Muamera; Singh, Alok R; Skola, Dylan; Glass, Christopher K; Sanders, P Dominick; Sharabi, Andrew B; Pham, Timothy V; Tamayo, Pablo; Shiang, Daniel; Dinh, Huy Q; Hedrick, Catherine C; Morales, Guillermo A; Garlich, Joseph R; Durden, Donald L

A Threshold Model for T-Cell Activation in the Era of Checkpoint Blockade Immunotherapy

检查点阻断免疫疗法时代T细胞活化的阈值模型

Guram, Kripa; Kim, Sangwoo S; Wu, Victoria; Sanders, P Dominick; Patel, Sandip; Schoenberger, Stephen P; Cohen, Ezra E W; Chen, Si-Yi; Sharabi, Andrew B

Radiation Therapy Combined With Checkpoint Blockade Immunotherapy for Metastatic Undifferentiated Pleomorphic Sarcoma of the Maxillary Sinus With a Complete Response

放射治疗联合免疫检查点阻断疗法治疗上颌窦转移性未分化多形性肉瘤,获得完全缓解

Guram, Kripa; Nunez, Maria; Einck, John; Mell, Loren K; Cohen, Ezra; Sanders, P Dominick; Miyauchi, Sayuri; Weihe, Elizabeth; Kurzrock, Razelle; Boles, Sarah; Sharabi, Andrew B

CD8+ T cells drive autoimmune hematopoietic stem cell dysfunction and bone marrow failure

CD8+ T 细胞驱动自身免疫性造血干细胞功能障碍和骨髓衰竭

David M Gravano, Mufadhal Al-Kuhlani, Dan Davini, P Dominick Sanders, Jennifer O Manilay, Katrina K Hoyer