日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Development of a Janus Kinase Inhibitor Prodrug for the Treatment of Rheumatoid Arthritis

开发用于治疗类风湿性关节炎的 Janus 激酶抑制剂前药

Xin Wei, Jianbo Wu, Gang Zhao, Josselyn Galdamez, Subodh M Lele, Xiaoyan Wang, Yanzhi Liu, Dhruvkumar M Soni, P Edward Purdue, Ted R Mikuls, Steven R Goldring, Dong Wang

HPMA-Copolymer Nanocarrier Targets Tumor-Associated Macrophages in Primary and Metastatic Breast Cancer

HPMA 共聚物纳米载体靶向原发性和转移性乳腺癌中的肿瘤相关巨噬细胞

Melissa N Zimel, Chloe B Horowitz, Vinagolu K Rajasekhar, Alexander B Christ, Xin Wei, Jianbo Wu, Paulina M Wojnarowicz, Dong Wang, Steven R Goldring, P Edward Purdue, John H Healey

Simvastatin prodrug micelles target fracture and improve healing

辛伐他汀前药胶束靶向骨折并促进愈合

Zhenshan Jia #, Yijia Zhang #, Yen Hsun Chen #, Anand Dusad, Hongjiang Yuan, Ke Ren, Fei Li, Edward V Fehringer, P Edward Purdue, Steven R Goldring, Aaron Daluiski, Dong Wang

Macromolecular prodrug of dexamethasone prevents particle-induced peri-implant osteolysis with reduced systemic side effects

地塞米松的大分子前药可防止颗粒诱发的种植体周围骨溶解,并减少全身副作用

Ke Ren, Anand Dusad, Fang Yuan, Hongjiang Yuan, P Edward Purdue, Edward V Fehringer, Kevin L Garvin, Steven R Goldring, Dong Wang

Comprehensive profiling analysis of actively resorbing osteoclasts identifies critical signaling pathways regulated by bone substrate

对主动吸收破骨细胞的综合分析确定了骨基质调控的关键信号通路

P Edward Purdue, Tania N Crotti, Zhenxin Shen, Jennifer Swantek, Jun Li, Jonathan Hill, Adedayo Hanidu, Janice Dimock, Gerald Nabozny, Steven R Goldring, Kevin P McHugh

Negative regulation of osteoclast precursor differentiation by CD11b and β2 integrin-B-cell lymphoma 6 signaling

CD11b 和 β2 整合素-B 细胞淋巴瘤 6 信号对破骨细胞前体分化的负向调节

Kyung-Hyun Park-Min, Eun Young Lee, Neal K Moskowitz, Elisha Lim, Sun-Kyeong Lee, Joseph A Lorenzo, Chuanxin Huang, Ari M Melnick, P Edward Purdue, Steven R Goldring, Lionel B Ivashkiv

Targeting the giant cell tumor stromal cell: functional characterization and a novel therapeutic strategy

靶向巨细胞瘤基质细胞:功能表征和新型治疗策略

Matthew R Steensma, Wakenda K Tyler, Allison G Shaber, Steven R Goldring, F Patrick Ross, Bart O Williams, John H Healey, P Edward Purdue

The relative timing of exposure to phagocytosable particulates and to osteoclastogenic cytokines is critically important in the determination of myeloid cell fate

暴露于可吞噬颗粒和破骨细胞因子的相对时间对于决定髓系细胞的命运至关重要

Douglas E James, Bryan J Nestor, Thomas P Sculco, Lionel B Ivashkiv, F Patrick Ross, Steven R Goldring, P Edward Purdue