The protease-activated receptor 4 Ala120Thr variant alters platelet responsiveness to low-dose thrombin and protease-activated receptor 4 desensitization, and is blocked by non-competitive P2Y12 inhibition
蛋白酶激活受体 4 Ala120Thr 变体会改变血小板对低剂量凝血酶和蛋白酶激活受体 4 脱敏的反应性,并被非竞争性 P2Y12 抑制所阻断
期刊:Journal of Thrombosis and Haemostasis
影响因子:5.5
doi:10.1111/jth.14318
M J Whitley, D M Henke, A Ghazi, M Nieman, M Stoller, L M Simon, E Chen, J Vesci, M Holinstat, S E McKenzie, C A Shaw, L C Edelstein, P F Bray