日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Small molecule SJ572946 activates BAK to initiate apoptosis

小分子SJ572946激活BAK启动细胞凋亡

Giridhar Sekar ,Geetika Singh ,Xingping Qin ,Cristina D Guibao ,Brittany Schwam ,Zintis Inde ,Christy R Grace ,Weixing Zhang ,P Jake Slavish ,Wenwei Lin ,Taosheng Chen ,Richard E Lee ,Zoran Rankovic ,Kristopher Sarosiek ,Tudor Moldoveanu

Identification of Potent, Selective, and Orally Bioavailable Small-Molecule GSPT1/2 Degraders from a Focused Library of Cereblon Modulators

从聚焦的 Cereblon 调节剂库中鉴定高效、选择性强且口服生物利用度高的小分子 GSPT1/2 降解剂

Gisele Nishiguchi,Fatemeh Keramatnia,Jaeki Min,Yunchao Chang,Barbara Jonchere,Sourav Das,Marisa Actis,Jeanine Price,Divyabharathi Chepyala,Brandon Young,Kevin McGowan,P Jake Slavish,Anand Mayasundari,Jamie A Jarusiewicz,Lei Yang,Yong Li,Xiang Fu,Shalandus H Garrett,James B Papizan,Kiran Kodali,Junmin Peng,Shondra M Pruett Miller,Martine F Roussel,Charles Mullighan,Marcus Fischer,Zoran Rankovic

Bromodomain-Selective BET Inhibitors Are Potent Antitumor Agents against MYC-Driven Pediatric Cancer

溴结构域选择性 BET 抑制剂是针对 MYC 驱动的儿童癌症的有效抗肿瘤药物

P Jake Slavish #, Liying Chi #, Mi-Kyung Yun #, Lyudmila Tsurkan #, Nancy E Martinez, Barbara Jonchere, Sergio C Chai, Michele Connelly, M Brett Waddell, Sourav Das, Geoffrey Neale, Zhenmei Li, William R Shadrick, Rachelle R Olsen, Kevin W Freeman, Jonathan A Low, Jeanine E Price, Brandon M Young, N

Structural and biochemical basis for development of influenza virus inhibitors targeting the PA endonuclease

针对 PA 核酸内切酶的流感病毒抑制剂开发的结构和生化基础

Rebecca M DuBois, P Jake Slavish, Brandi M Baughman, Mi-Kyung Yun, Ju Bao, Richard J Webby, Thomas R Webb, Stephen W White