日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Pooled Knockin Targeting for Genome Engineering of Cellular Immunotherapies

用于细胞免疫疗法基因组工程的联合敲入靶向

Theodore L Roth ,P Jonathan Li ,Franziska Blaeschke ,Jasper F Nies ,Ryan Apathy ,Cody Mowery ,Ruby Yu ,Michelle L T Nguyen ,Youjin Lee ,Anna Truong ,Joseph Hiatt ,David Wu ,David N Nguyen ,Daniel Goodman ,Jeffrey A Bluestone ,Chun Jimmie Ye ,Kole Roybal ,Eric Shifrut ,Alexander Marson

Polymer-stabilized Cas9 nanoparticles and modified repair templates increase genome editing efficiency

聚合物稳定的Cas9纳米粒子和修饰的修复模板提高了基因组编辑效率

David N Nguyen #, Theodore L Roth #, P Jonathan Li, Peixin Amy Chen, Ryan Apathy, Murad R Mamedov, Linda T Vo, Victoria R Tobin, Daniel Goodman, Eric Shifrut, Jeffrey A Bluestone, Jennifer M Puck, Francis C Szoka, Alexander Marson

Reprogramming human T cell function and specificity with non-viral genome targeting

利用非病毒基因组靶向技术重编程人类T细胞功能和特异性

Theodore L Roth,Cristina Puig-Saus,Ruby Yu,Eric Shifrut,Julia Carnevale,P Jonathan Li,Joseph Hiatt,Justin Saco,Paige Krystofinski,Han Li,Victoria Tobin,David N Nguyen,Michael R Lee,Amy L Putnam,Andrea L Ferris,Jeff W Chen,Jean-Nicolas Schickel,Laurence Pellerin,David Carmody,Gorka Alkorta-Aranburu,Daniela Del Gaudio,Hiroyuki Matsumoto,Montse Morell,Ying Mao,Min Cho,Rolen M Quadros,Channabasavaiah B Gurumurthy,Baz Smith,Michael Haugwitz,Stephen H Hughes,Jonathan S Weissman,Kathrin Schumann,Jonathan H Esensten,Andrew P May,Alan Ashworth,Gary M Kupfer,Siri Atma W Greeley,Rosa Bacchetta,Eric Meffre,Maria Grazia Roncarolo,Neil Romberg,Kevan C Herold,Antoni Ribas,Manuel D Leonetti,Alexander Marson

Genome-wide CRISPR Screens in Primary Human T Cells Reveal Key Regulators of Immune Function

利用全基因组 CRISPR 技术筛选原代人 T 细胞,揭示免疫功能的关键调控因子

Eric Shifrut # ,Julia Carnevale # ,Victoria Tobin ,Theodore L Roth ,Jonathan M Woo ,Christina T Bui ,P Jonathan Li ,Morgan E Diolaiti ,Alan Ashworth ,Alexander Marson

Tumor-derived CSF-1 induces the NKG2D ligand RAE-1δ on tumor-infiltrating macrophages

肿瘤来源的 CSF-1 诱导肿瘤浸润巨噬细胞表达 NKG2D 配体 RAE-1δ

Thornton W Thompson ,Benjamin T Jackson ,P Jonathan Li ,Jiaxi Wang ,Alexander Byungsuk Kim ,Kristen Ting Hui Huang ,Lily Zhang ,David H Raulet

Endothelial cells express NKG2D ligands and desensitize antitumor NK responses

内皮细胞表达NKG2D配体,并使抗肿瘤NK细胞反应脱敏。

Thornton W Thompson ,Alexander Byungsuk Kim ,P Jonathan Li ,Jiaxi Wang ,Benjamin T Jackson ,Kristen Ting Hui Huang ,Lily Zhang ,David H Raulet