Phase II trial with nivolumab and sorafenib in HCC identified enrichment of immunosuppressive monocytes in patients with Child-Pugh B liver dysfunction
一项针对肝细胞癌患者的II期临床试验(使用纳武利尤单抗联合索拉非尼)发现,Child-Pugh B级肝功能障碍患者体内免疫抑制性单核细胞富集。
期刊:Jhep Reports
影响因子:7.5
doi:10.1016/j.jhepr.2026.101817
Keenan, Bridget P; Fan, Zenghua; Le, Bryan Khuong; Harris, Quincy; Chen, Jocelin; Clark, Matthew; Lea, Averey; Zhang, Li; Cheung, Alexander; Lara, Frances; Gordan, John D; Bracci, Paige; Behr, Spencer C; Fong, Lawrence; Venook, Alan P; Kim, Edward J; Kelley, Robin K