日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

A fluid biomarker reveals loss of TDP-43 splicing repression in presymptomatic ALS-FTD

液体生物标志物揭示了 ALS-FTD 症状前 TDP-43 剪接抑制的丧失

Katherine E Irwin, Pei Jasin, Kerstin E Braunstein, Irika R Sinha, Mark A Garret, Kyra D Bowden, Koping Chang, Juan C Troncoso, Abhay Moghekar, Esther S Oh, Denitza Raitcheva, Dan Bartlett, Timothy Miller, James D Berry, Bryan J Traynor, Jonathan P Ling, Philip C Wong

Multivalent GU-rich oligonucleotides sequester TDP-43 in the nucleus by inducing high molecular weight RNP complexes

多价富含 GU 的寡核苷酸通过诱导高分子量 RNP 复合物将 TDP-43 隔离在细胞核中

Xi Zhang, Tanuza Das, Tiffany F Chao, Vickie Trinh, Rogger P Carmen-Orozco, Jonathan P Ling, Petr Kalab, Lindsey R Hayes

Large-scale RNA-seq mining reveals ciclopirox triggers TDP-43 cryptic exons

大规模 RNA 测序挖掘显示环吡咯酮可触发 TDP-43 隐秘外显子

Irika R Sinha, Parker S Sandal, Grace D Burns, Aswathy Peethambaran Mallika, Katherine E Irwin, Anna Lourdes F Cruz, Vania Wang, Josué Llamas Rodríguez, Philip C Wong, Jonathan P Ling

Duration of antiretroviral therapy impacts the degree of residual SIV infection in the gut in long-term non-progressing Chinese rhesus macaques

抗逆转录病毒疗法的持续时间会影响长期非进展性中国恒河猴肠道内SIV残留感染的程度。

Solis-Leal, Antonio; May, Ann-Marie; Mohan, Mahesh; Dufour, Jason P; Ling, Binhua

A fluid biomarker reveals loss of TDP-43 splicing repression in pre-symptomatic ALS

液体生物标志物揭示了 ALS 症状前 TDP-43 剪接抑制的丧失

Katherine E Irwin, Pei Jasin, Kerstin E Braunstein, Irika Sinha, Kyra D Bowden, Abhay Moghekar, Esther S Oh, Denitza Raitcheva, Dan Bartlett, James D Berry, Bryan Traynor, Jonathan P Ling, Philip C Wong

Bismuth-Mediated α-Arylation of Acidic Diketones with ortho-Substituted Boronic Acids

铋介导的酸性二酮与邻位取代硼酸的α-芳基化反应

Ruffell, Katie; Argent, Stephen P; Ling, Kenneth B; Ball, Liam T

Loss of TDP-43 function and rimmed vacuoles persist after T cell depletion in a xenograft model of sporadic inclusion body myositis

在散发性包涵体肌炎异种移植模型中,TDP-43 功能丧失和边缘空泡在 T 细胞耗竭后持续存在

Kyla A Britson, Jonathan P Ling, Kerstin E Braunstein, Janelle M Montagne, Jenna M Kastenschmidt, Andrew Wilson, Chiseko Ikenaga, William Tsao, Iago Pinal-Fernandez, Katelyn A Russell, Nicole Reed, Tahseen Mozaffar, Kathryn R Wagner, Lyle W Ostrow, Andrea M Corse, Andrew L Mammen, S Armando Villalta

Amyloid-beta and tau pathologies act synergistically to induce novel disease stage-specific microglia subtypes

淀粉样β蛋白和tau蛋白病理协同作用,诱导新的疾病阶段特异性小胶质细胞亚型

Dong Won Kim, Kevin J Tu, Alice Wei, Ashley J Lau, Anabel Gonzalez-Gil, Tianyu Cao, Kerstin Braunstein, Jonathan P Ling, Juan C Troncoso, Philip C Wong, Seth Blackshaw, Ronald L Schnaar, Tong Li

Cell-specific regulation of gene expression using splicing-dependent frameshifting

利用剪接依赖性移码技术进行细胞特异性基因表达调控

Jonathan P Ling #, Alexei M Bygrave #, Clayton P Santiago #, Rogger P Carmen-Orozco, Vickie T Trinh, Minzhong Yu, Yini Li, Ying Liu, Kyra D Bowden, Leighton H Duncan, Jeong Han, Kamil Taneja, Rochinelle Dongmo, Travis A Babola, Patrick Parker, Lizhi Jiang, Patrick J Leavey, Jennifer J Smith, Rachel

Stage-specific control of oligodendrocyte survival and morphogenesis by TDP-43

TDP-43 对少突胶质细胞存活和形态发生的阶段特异性控制

Dongeun Heo, Jonathan P Ling, Gian C Molina-Castro, Abraham J Langseth, Ari Waisman, Klaus-Armin Nave, Wiebke Möbius, Phil C Wong, Dwight E Bergles