日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Evaluation of a biomarker for amyotrophic lateral sclerosis derived from a hypomethylated DNA signature of human motor neurons

评估源自人类运动神经元低甲基化DNA特征的肌萎缩侧索硬化症生物标志物

Harvey, Calum; Nowak, Alicja; Zhang, Sai; Moll, Tobias; Weimer, Annika K; Barcons, Aina Mogas; Dos Santos Souza, Cleide; Ferraiuolo, Laura; Kenna, Kevin; Zaitlen, Noah; Caggiano, Christa; Shaw, Pamela J; Snyder, Michael P; Mill, Jonathan; Hannon, Eilis; Cooper-Knock, Johnathan

Causal linkage of presence of mutant NPM1 to efficacy of novel therapeutic agents against AML cells with mutant NPM1

突变型 NPM1 的存在与新型治疗药物对具有突变型 NPM1 的 AML 细胞的疗效存在因果关系

Christopher P Mill #, Warren Fiskus #, Kaberi Das, John A Davis, Christine E Birdwell, Tapan M Kadia, Courtney D DiNardo, Naval Daver, Koichi Takahashi, Koji Sasaki, Gerard M McGeehan, Xinjia Ruan, Xiaoping Su, Sanam Loghavi, Hagop Kantarjian, Kapil N Bhalla

Effective Menin inhibitor-based combinations against AML with MLL rearrangement or NPM1 mutation (NPM1c)

针对 MLL 重排或 NPM1 突变 (NPM1c) 的 AML 的有效 Menin 抑制剂组合

Warren Fiskus, Steffen Boettcher, Naval Daver, Christopher P Mill, Koji Sasaki, Christine E Birdwell, John A Davis, Koichi Takahashi, Tapan M Kadia, Courtney D DiNardo, Qi Jin, Yuan Qi, Xiaoping Su, Gerard M McGeehan, Joseph D Khoury, Benjamin L Ebert, Kapil N Bhalla

BET proteolysis targeted chimera-based therapy of novel models of Richter Transformation-diffuse large B-cell lymphoma

针对 Richter 转化型弥漫大 B 细胞淋巴瘤新型模型的 BET 蛋白水解靶向嵌合体治疗

Warren Fiskus #, Christopher P Mill #, Dimuthu Perera, Christine Birdwell, Qing Deng, Haopeng Yang, Bernardo H Lara, Nitin Jain, Jan Burger, Alessandra Ferrajoli, John A Davis, Dyana T Saenz, Wendy Jin, Cristian Coarfa, Craig M Crews, Michael R Green, Joseph D Khoury, Kapil N Bhalla

Independent Methylome-Wide Association Studies of Schizophrenia Detect Consistent Case-Control Differences

精神分裂症的独立甲基化组关联研究检测到一致的病例对照差异

Chan, Robin F; Shabalin, Andrey A; Montano, Carolina; Hannon, Eilis; Hultman, Christina M; Fallin, Margaret D; Feinberg, Andrew P; Mill, Jonathan; van den Oord, Edwin J C G; Aberg, Karolina A

Development and application of high-throughput screens for the discovery of compounds that disrupt ErbB4 signaling: Candidate cancer therapeutics

开发和应用高通量筛选来发现破坏 ErbB4 信号传导的化合物:候选癌症治疗药物

Richard L Cullum, Lauren M Lucas, Jared I Senfeld, John T Piazza, Logan T Neel, Kanupriya Whig, Ling Zhai, Mackenzie H Harris, Cristina C Rael, Darby C Taylor, Laura J Cook, David P Kaufmann, Christopher P Mill, Megan A Jacobi, Forrest T Smith, Mark Suto, Robert Bostwick, Ram B Gupta, Allan E David,

Superior efficacy of cotreatment with BET protein inhibitor and BCL2 or MCL1 inhibitor against AML blast progenitor cells

BET 蛋白抑制剂与 BCL2 或 MCL1 抑制剂联合治疗对 AML 原始细胞祖细胞具有更优疗效

Warren Fiskus, Tianyu Cai, Courtney D DiNardo, Steven M Kornblau, Gautam Borthakur, Tapan M Kadia, Naveen Pemmaraju, Prithviraj Bose, Lucia Masarova, Kimal Rajapakshe, Dimuthu Perera, Cristian Coarfa, Christopher P Mill, Dyana T Saenz, David N Saenz, Baohua Sun, Joseph D Khoury, Yu Shen, Marina Kono

Prevalence of pelagic dependence among coral reef predators across an atoll seascape

环礁海域珊瑚礁捕食者对远洋生物的依赖性普遍存在

Skinner, Christina; Newman, Steven P; Mill, Aileen C; Newton, Jason; Polunin, Nicholas V C

Dynamic Regulation of Long-Chain Fatty Acid Oxidation by a Noncanonical Interaction between the MCL-1 BH3 Helix and VLCAD

MCL-1 BH3螺旋与VLCAD之间非经典相互作用对长链脂肪酸氧化的动态调控

Silvia Escudero ,Elma Zaganjor ,Susan Lee ,Christopher P Mill ,Ann M Morgan ,Emily B Crawford ,Jiahao Chen ,Thomas E Wales ,Rida Mourtada ,James Luccarelli ,Gregory H Bird ,Ulrich Steidl ,John R Engen ,Marcia C Haigis ,Joseph T Opferman ,Loren D Walensky

SIRT2 Deacetylates and Inhibits the Peroxidase Activity of Peroxiredoxin-1 to Sensitize Breast Cancer Cells to Oxidant Stress-Inducing Agents

SIRT2 脱乙酰化并抑制过氧化物酶-1 的过氧化物酶活性,使乳腺癌细胞对氧化应激诱导剂敏感

Warren Fiskus, Veena Coothankandaswamy, Jianguang Chen, Hongwei Ma, Kyungsoo Ha, Dyana T Saenz, Stephanie S Krieger, Christopher P Mill, Baohua Sun, Peng Huang, Jeffrey S Mumm, Ari M Melnick, Kapil N Bhalla