日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Somatic human ZBTB7A zinc finger mutations promote cancer progression

人类体细胞 ZBTB7A 锌指突变促进癌症进展

X-S Liu, Z Liu, C Gerarduzzi, D E Choi, S Ganapathy, P P Pandolfi, Z-M Yuan

TSPYL2 is an essential component of the REST/NRSF transcriptional complex for TGFβ signaling activation

TSPYL2 是 REST/NRSF 转录复合物中 TGFβ 信号激活的重要组成部分

M T Epping, A Lunardi, D Nachmani, M Castillo-Martin, T H Thin, C Cordon-Cardo, P P Pandolfi

BCR-ABL disrupts PTEN nuclear-cytoplasmic shuttling through phosphorylation-dependent activation of HAUSP

BCR-ABL 通过磷酸化依赖的 HAUSP 激活来破坏 PTEN 的核质穿梭

A Morotti, C Panuzzo, S Crivellaro, B Pergolizzi, U Familiari, A H Berger, G Saglio, P P Pandolfi

ATM kinase enables the functional axis of YAP, PML and p53 to ameliorate loss of Werner protein-mediated oncogenic senescence

ATM 激酶使 YAP、PML 和 p53 的功能轴改善 Werner 蛋白介导的致癌衰老的丧失

F Fausti, S Di Agostino, M Cioce, P Bielli, C Sette, P P Pandolfi, M Oren, M Sudol, S Strano, G Blandino

Cell death induced by dexamethasone in lymphoid leukemia is mediated through initiation of autophagy

地塞米松诱导的淋巴细胞白血病细胞死亡是通过启动自噬介导的

E Laane, K Pokrovskaja Tamm, E Buentke, K Ito, P Kharaziha, J Oscarsson, M Corcoran, A-C Björklund, K Hultenby, J Lundin, M Heyman, S Söderhäll, J Mazur, A Porwit, P P Pandolfi, B Zhivotovsky, T Panaretakis, D Grandér

Histone deacetylase inhibitors induce remission in transgenic models of therapy-resistant acute promyelocytic leukemia

组蛋白去乙酰化酶抑制剂可诱导治疗耐药性急性早幼粒细胞白血病转基因模型缓解

L Z He, T Tolentino, P Grayson, S Zhong, R P Warrell Jr, R A Rifkind, P A Marks, V M Richon, P P Pandolfi

p62(dok), a negative regulator of Ras and mitogen-activated protein kinase (MAPK) activity, opposes leukemogenesis by p210(bcr-abl)

p62(dok) 是 Ras 和丝裂原活化蛋白激酶 (MAPK) 活性的负调节剂,可抑制 p210(bcr-abl) 引起的白血病形成

A Di Cristofano, M Niki, M Zhao, F G Karnell, B Clarkson, W S Pear, L Van Aelst, P P Pandolfi

FES-Cre targets phosphatidylinositol glycan class A (PIGA) inactivation to hematopoietic stem cells in the bone marrow

FES-Cre 靶向磷脂酰肌醇聚糖 A 类 (PIGA) 失活,进而导致骨髓造血干细胞

P Keller, J L Payne, G Tremml, P A Greer, M Gaboli, P P Pandolfi, M Bessler

Altered myelopoiesis and the development of acute myeloid leukemia in transgenic mice overexpressing cyclin A1

过表达细胞周期蛋白 A1 的转基因小鼠发生骨髓细胞生成改变和急性髓系白血病的发展

C Liao, X Y Wang, H Q Wei, S Q Li, T Merghoub, P P Pandolfi, D J Wolgemuth

Promyelocytic leukemia protein (PML) and Daxx participate in a novel nuclear pathway for apoptosis

早幼粒细胞白血病蛋白 (PML) 和 Daxx 参与细胞凋亡的新型核通路

S Zhong, P Salomoni, S Ronchetti, A Guo, D Ruggero, P P Pandolfi