CSF1R inhibition rescues tau pathology and neurodegeneration in an A/T/N model with combined AD pathologies, while preserving plaque associated microglia
CSF1R 抑制可挽救患有 AD 病理的 A/T/N 模型中的 tau 病理和神经退行性病变,同时保留斑块相关的小胶质细胞
期刊:Acta Neuropathologica Communications
影响因子:6.2
doi:10.1186/s40478-021-01204-8
Chritica Lodder #, Isabelle Scheyltjens #, Ilie Cosmin Stancu #, Pablo Botella Lucena, Manuel Gutiérrez de Ravé, Sarah Vanherle, Tim Vanmierlo, Niels Cremers, Hannah Vanrusselt, Bert Brône, Bernard Hanseeuw, Jean-Noël Octave, Astrid Bottelbergs, Kiavash Movahedi #, Ilse Dewachter #2