Upregulation of the AMPK-FOXO1-PDK4 pathway is a primary mechanism of pyruvate dehydrogenase activity reduction in tafazzin-deficient cells
AMPK-FOXO1-PDK4 通路的上调是 tafazzin 缺乏细胞中丙酮酸脱氢酶活性降低的主要机制
期刊:Scientific Reports
影响因子:3.8
doi:10.1038/s41598-024-62262-1
Zhuqing Liang, Tyler Ralph-Epps, Michael W Schmidtke, Pablo Lazcano, Simone W Denis, Mária Balážová, Nevton Teixeira da Rosa Jr, Mohamed Chakkour, Sanaa Hazime, Mindong Ren, Michael Schlame, Riekelt H Houtkooper, Miriam L Greenberg