日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Infection of 5xFAD mice with a mouse-adapted SARS-CoV-2 does not alter Alzheimer's disease neuropathology yet induces widespread changes in gene expression across diverse cell types

用小鼠适应性SARS-CoV-2感染5xFAD小鼠不会改变阿尔茨海默病神经病理学,但会诱导多种细胞类型中基因表达的广泛变化。

Furman, Susana; Zayou, Latifa; Tsourmas, Kate Inman; Javonillo, Dominic Ibarra; Olivarria, Gema M; Cheng, Yuting; Pachow, Collin; Fernandez, Kellie; Le, Lucas; Edwards, Robert A; Nicholas, Dequina A; Sanchez, Gabriela Pacheco; Baric, Ralph S; Green, Kim N; Lane, Thomas E

Identification of the velum interpositum as a meningeal-CNS route for myeloid cell trafficking into the brain

确定脑膜间膜是髓系细胞进入大脑的脑膜-中枢神经系统途径

Lindsay A Hohsfield ,Sung Jin Kim ,Rocio A Barahona ,Caden M Henningfield ,Kimiya Mansour ,Kristen D Vallejo ,Kate I Tsourmas ,Nellie E Kwang ,Yasamine Ghorbanian ,Julio Alejandro Ayala Angulo ,Pan Gao ,Collin Pachow ,Matthew A Inlay ,Craig M Walsh ,Xiangmin Xu ,Thomas E Lane ,Kim N Green

Infection of 5xFAD mice with a mouse-adapted SARS-CoV-2 does not alter Alzheimer's disease neuropathology yet induces wide-spread changes in gene expression across diverse cell types.

用小鼠适应性 SARS-CoV-2 感染 5xFAD 小鼠不会改变阿尔茨海默病神经病理学,但会引发多种细胞类型中基因表达的广泛变化。

Furman Susana, Zayou Latifa, Tsourmas Kate Inman, Javonillo Dominic Ibarra, Olivarria Gema M, Cheng Yuting, Pachow Collin, Fernandez Kellie, Le Lucas, Edwards Robert A, Nicholas Dequina A, Sanchez Gabriela Pacheco, Baric Ralph S, Green Kim N, Lane Thomas E

Cystatin F attenuates neuroinflammation and demyelination following murine coronavirus infection of the central nervous system

胱抑素F可减轻小鼠冠状病毒感染中枢神经系统后的神经炎症和脱髓鞘。

Amber R Syage ,Collin Pachow ,Kaitlin M Murray ,Caden Henningfield ,Kellie Fernandez ,Annie Du ,Yuting Cheng ,Gema Olivarria ,Shimako Kawauchi ,Grant R MacGregor ,Kim N Green ,Thomas E Lane

Microglia influence immune responses and restrict neurologic disease in response to central nervous system infection by a neurotropic murine coronavirus

小胶质细胞影响免疫反应,并能抑制由嗜神经性鼠冠状病毒引起的中枢神经系统感染所导致的神经系统疾病。

Syage, Amber; Pachow, Collin; Cheng, Yuting; Mangale, Vrushali; Green, Kim N; Lane, Thomas E

Ablation of microglia following infection of the central nervous system with a neurotropic murine coronavirus infection leads to increased demyelination and impaired remyelination

中枢神经系统感染神经性鼠冠状病毒后,小胶质细胞消融会导致脱髓鞘增加和髓鞘再生受损

Yuting Cheng, Dominic Ibarra Javonillo, Collin Pachow, Vanessa M Scarfone, Kellie Fernandez, Craig M Walsh, Kim N Green, Thomas E Lane

Microglia Do Not Restrict SARS-CoV-2 Replication following Infection of the Central Nervous System of K18-Human ACE2 Transgenic Mice

在K18-人ACE2转基因小鼠中枢神经系统感染后,小胶质细胞并不限制SARS-CoV-2的复制

Olivarria, Gema M; Cheng, Yuting; Furman, Susana; Pachow, Collin; Hohsfield, Lindsay A; Smith-Geater, Charlene; Miramontes, Ricardo; Wu, Jie; Burns, Mara S; Tsourmas, Kate I; Stocksdale, Jennifer; Manlapaz, Cynthia; Yong, William H; Teijaro, John; Edwards, Robert; Green, Kim N; Thompson, Leslie M; Lane, Thomas E

Early detection of tumor cells in bone marrow and peripheral blood in a fast‑progressing gastric cancer model

快速进展的胃癌模型中骨髓和外周血中肿瘤细胞的早期检测

Prerna Bali, Ivonne Lozano-Pope, Collin Pachow, Marygorret Obonyo

Microglia do not restrict SARS-CoV-2 replication following infection of the central nervous system of K18-hACE2 transgenic mice

在K18-hACE2转基因小鼠中枢神经系统感染后,小胶质细胞并不抑制SARS-CoV-2的复制。

Olivarria, Gema M; Cheng, Yuting; Furman, Susana; Pachow, Collin; Hohsfield, Lindsay A; Smith-Geater, Charlene; Miramontes, Ricardo; Wu, Jie; Burns, Mara S; Tsourmas, Kate I; Stocksdale, Jennifer; Manlapaz, Cynthia; Yong, William H; Teijaro, John; Edwards, Robert; Green, Kim N; Thompson, Leslie M; Lane, Thomas E

The mTOR signaling pathway as a treatment target for intracranial neoplasms

mTOR信号通路作为颅内肿瘤的治疗靶点

Pachow, Doreen; Wick, Wolfgang; Gutmann, David H; Mawrin, Christian