日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Hydrogel-Bead Particles Enable Activity-Based Identification of Nucleic Acid Aptamer Enzyme Inhibitors

水凝胶微珠颗粒可实现基于活性的核酸适体酶抑制剂鉴定

Nguyen, Amanda A; Paegel, Brian M

Activity-Based DNA-Encoded Library Screening for Selective Inhibitors of Eukaryotic Translation

基于活性的DNA编码文库筛选真核翻译选择性抑制剂

Barhoosh, Huda; Dixit, Anjali; Cochrane, Wesley G; Cavett, Valerie; Prince, Robin N; Blair, Brooke O; Ward, Fred R; McClure, Kim F; Patten, Phillip A; Paulick, Margot G; Paegel, Brian M

Building Block-Centric Approach to DNA-Encoded Library Design

基于构建模块的DNA编码文库设计方法

Fitzgerald, Patrick R; Dixit, Anjali; Zhang, Chris; Mobley, David L; Paegel, Brian M

Translating the Genome into Drugs

将基因组转化为药物

Dixit, Anjali; Barhoosh, Huda; Paegel, Brian M

Hydrogel-Encapsulated Beads Enable Proximity-Driven Encoded Library Synthesis and Screening

水凝胶包裹的微珠可实现邻近驱动的编码文库合成和筛选

Cavett, Valerie; Chan, Alix I; Cunningham, Christian N; Paegel, Brian M

Liposomal Permeation Assay for Droplet-Scale Pharmacokinetic Screening

用于液滴级药代动力学筛选的脂质体渗透试验

Juan Hu, Alix I Chan, Emel Adaligil, Ivy Kekessie, Mifune Takahashi, Aimin Song, Christian N Cunningham, Brian M Paegel

Study of an RNA-Focused DNA-Encoded Library Informs Design of a Degrader of a r(CUG) Repeat Expansion

一项针对RNA的DNA编码文库的研究为ar(CUG)重复序列扩增降解剂的设计提供了信息

Gibaut, Quentin M R; Akahori, Yoshihiro; Bush, Jessica A; Taghavi, Amirhossein; Tanaka, Toru; Aikawa, Haruo; Ryan, Lucas S; Paegel, Brian M; Disney, Matthew D

DNA-encoded library versus RNA-encoded library selection enables design of an oncogenic noncoding RNA inhibitor

DNA编码文库与RNA编码文库的筛选方法能够设计致癌性非编码RNA抑制剂。

Benhamou, Raphael I; Suresh, Blessy M; Tong, Yuquan; Cochrane, Wesley G; Cavett, Valerie; Vezina-Dawod, Simon; Abegg, Daniel; Childs-Disney, Jessica L; Adibekian, Alexander; Paegel, Brian M; Disney, Matthew D

DNA-Encoded Chemistry: Drug Discovery from a Few Good Reactions

DNA编码化学:从少数有效反应中发现药物

Fitzgerald, Patrick R; Paegel, Brian M

Chiral lipid bilayers are enantioselectively permeable

手性脂质双层膜具有对映选择性渗透性

Hu, Juan; Cochrane, Wesley G; Jones, Alexander X; Blackmond, Donna G; Paegel, Brian M