Pagano Patrick J相关文献与解析，生知库 | 链接生命科学的每一步

Redox regulation of lung endothelial PERK, unfolded protein response (UPR) and proliferation via NOX1: Targeted inhibition as a potential therapy for PAH.

通过 NOX1 调节肺内皮细胞 PERK、未折叠蛋白反应 (UPR) 和增殖的氧化还原反应：靶向抑制作为 PAH 的潜在疗法

doi:10.1016/j.redox.2025.103554

Goossen Christian J, Kufner Alex, Dustin Christopher M, Al Ghouleh Imad, Yuan Shuai, Straub Adam C, Sembrat John, Baust Jeffrey J, Gomez Delphine, KraÄun Damir, Pagano Patrick J

细胞生物学

发表日期：2025

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NOX2 in Alzheimer's and Parkinson's disease

NOX2 在阿尔茨海默病和帕金森病中的作用

期刊:Redox Biology

影响因子:11.9

doi:10.1016/j.redox.2024.103433

Dustin, Christopher M; Shiva, Sruti S; Vazquez, Alberto; Saeed, Anum; Pascoal, Tharick; Cifuentes-Pagano, Eugenia; Pagano, Patrick J

Role of the CCL5 and Its Receptor, CCR5, in the Genesis of Aldosterone-Induced Hypertension, Vascular Dysfunction, and End-Organ Damage

CCL5及其受体CCR5在醛固酮诱导的高血压、血管功能障碍和终末器官损伤发生中的作用

期刊:Hypertension

影响因子:8.2

doi:10.1161/HYPERTENSIONAHA.123.21888

Costa, Rafael M; Cerqueira, Débora M; Bruder-Nascimento, Ariane; Alves, Juliano V; Awata, Wanessa M C; Singh, Shubhnita; Kufner, Alexander; Prado, Douglas S; Johny, Ebin; Cifuentes-Pagano, Eugenia; Hawse, William F; Dutta, Partha; Pagano, Patrick J; Ho, Jacqueline; Bruder-Nascimento, Thiago

Pannexin-3 stabilizes the transcription factor Bcl6 in a channel-independent manner to protect against vascular oxidative stress.

Pannexin-3 以不依赖通道的方式稳定转录因子 Bcl6，从而防止血管氧化应激

期刊:Science Signaling

影响因子:6.6

doi:10.1126/scisignal.adg2622

Wolpe Abigail G, Luse Melissa A, Baryiames Christopher, Schug Wyatt J, Wolpe Jacob B, Johnstone Scott R, Dunaway Luke S, JuÅkiewicz Zuzanna J, Loeb Skylar A, Askew Page Henry R, Chen Yen-Lin, Sabapathy Vikram, Pavelec Caitlin M, Wakefield Brent, Cifuentes-Pagano Eugenia, Artamonov Mykhaylo V, Somlyo Avril V, Straub Adam C, Sharma Rahul, Beier Frank, Barrett Eugene J, Leitinger Norbert, Pagano Patrick J, Sonkusare Swapnil K, Redemann Stefanie, Columbus Linda, Penuela Silvia, Isakson Brant E

Peripheral Ischemia Imprints Epigenetic Changes in Hematopoietic Stem Cells to Propagate Inflammation and Atherosclerosis

外周缺血在造血干细胞中引起表观遗传变化，从而促进炎症和动脉粥样硬化

期刊:Arteriosclerosis Thrombosis and Vascular Biology

影响因子:7.4

doi:10.1161/ATVBAHA.123.318956

Emilie Coppin #, Xinyi Zhang #, Lee Ohayon #, Ebin Johny, Ankush Dasari, Kang H Zheng, Lotte Stiekema, Eugenia Cifuentes-Pagano, Patrick J Pagano, Srilakshmi Chaparala, Erik S Stroes, Partha Dutta1

表观遗传

动脉粥样硬化

干细胞

Immunology/Inflammation

发表日期：2023

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Role Of The C-C Motif Chemokine Ligand 5 (CCL5) And Its Receptor, C-C Motif Chemokine Receptor 5 (CCR5) In The Genesis Of Aldosterone-induced Hypertension, Vascular Dysfunction, And End-organ Damage

CC 基序趋化因子配体 5 (CCL5) 及其受体 CC 基序趋化因子受体 5 (CCR5) 在醛固酮诱发的高血压、血管功能障碍和终末器官损伤的发生中的作用

期刊:

影响因子:

doi:10.1101/2023.09.22.558020

Rafael M Costa, Débora M Cerqueira, Ariane Bruder-Nascimento, Juliano V Alves, Wanessa A C Awata, Shubhnita Singh, Alexander Kufner, Eugenia Cifuentes-Pagano, Patrick J Pagano, Jacqueline Ho, Thiago Bruder-Nascimento

NADPH oxidase 2 activity in Parkinson's disease

帕金森病中的 NADPH 氧化酶 2 活性

期刊:Neurobiology of Disease

影响因子:5.1

doi:10.1016/j.nbd.2022.105754

Matthew T Keeney, Eric K Hoffman, Kyle Farmer, Christopher R Bodle, Marco Fazzari, Alevtina Zharikov, Sandra L Castro, Xiaoping Hu, Amanda Mortimer, Julia K Kofler, Eugenia Cifuentes-Pagano, Patrick J Pagano, Edward A Burton, Teresa G Hastings, J Timothy Greenamyre, Roberto Di Maio

Specificity Protein 1-Mediated Promotion of CXCL12 Advances Endothelial Cell Metabolism and Proliferation in Pulmonary Hypertension

特异性蛋白 1 介导的 CXCL12 促进肺动脉高压中的内皮细胞代谢和增殖

期刊:Antioxidants

影响因子:

doi:10.3390/antiox12010071

Evan R DeVallance, Christopher M Dustin, Daniel Simoes de Jesus, Imad Al Ghouleh, John C Sembrat, Eugenia Cifuentes-Pagano, Patrick J Pagano

Forestalling age-impaired angiogenesis and blood flow by targeting NOX: Interplay of NOX1, IL-6, and SASP in propagating cell senescence

通过靶向NOX来预防年龄相关的血管生成和血流受损：NOX1、IL-6和SASP在细胞衰老传播中的相互作用

期刊:Proceedings of the National Academy of Sciences of the United States of America

影响因子:9.1

doi:10.1073/pnas.2015666118

Li, Yao; Kračun, Damir; Dustin, Christopher M; El Massry, Mohamed; Yuan, Shuai; Goossen, Christian J; DeVallance, Evan R; Sahoo, Sanghamitra; St Hilaire, Cynthia; Gurkar, Aditi U; Finkel, Toren; Straub, Adam C; Cifuentes-Pagano, Eugenia; Pagano, Patrick J

NADPH oxidases: redox regulation of cell homeostasis and disease

NADPH氧化酶：细胞稳态和疾病的氧化还原调控

Redox regulation of lung endothelial PERK, unfolded protein response (UPR) and proliferation via NOX1: Targeted inhibition as a potential therapy for PAH.

通过 NOX1 调节肺内皮细胞 PERK、未折叠蛋白反应 (UPR) 和增殖的氧化还原反应：靶向抑制作为 PAH 的潜在疗法

NOX2 in Alzheimer's and Parkinson's disease

NOX2 在阿尔茨海默病和帕金森病中的作用

Role of the CCL5 and Its Receptor, CCR5, in the Genesis of Aldosterone-Induced Hypertension, Vascular Dysfunction, and End-Organ Damage

CCL5及其受体CCR5在醛固酮诱导的高血压、血管功能障碍和终末器官损伤发生中的作用

Pannexin-3 stabilizes the transcription factor Bcl6 in a channel-independent manner to protect against vascular oxidative stress.

Pannexin-3 以不依赖通道的方式稳定转录因子 Bcl6，从而防止血管氧化应激

Peripheral Ischemia Imprints Epigenetic Changes in Hematopoietic Stem Cells to Propagate Inflammation and Atherosclerosis

外周缺血在造血干细胞中引起表观遗传变化，从而促进炎症和动脉粥样硬化

Role Of The C-C Motif Chemokine Ligand 5 (CCL5) And Its Receptor, C-C Motif Chemokine Receptor 5 (CCR5) In The Genesis Of Aldosterone-induced Hypertension, Vascular Dysfunction, And End-organ Damage

CC 基序趋化因子配体 5 (CCL5) 及其受体 CC 基序趋化因子受体 5 (CCR5) 在醛固酮诱发的高血压、血管功能障碍和终末器官损伤的发生中的作用

NADPH oxidase 2 activity in Parkinson's disease

帕金森病中的 NADPH 氧化酶 2 活性

Specificity Protein 1-Mediated Promotion of CXCL12 Advances Endothelial Cell Metabolism and Proliferation in Pulmonary Hypertension

特异性蛋白 1 介导的 CXCL12 促进肺动脉高压中的内皮细胞代谢和增殖

Forestalling age-impaired angiogenesis and blood flow by targeting NOX: Interplay of NOX1, IL-6, and SASP in propagating cell senescence

通过靶向NOX来预防年龄相关的血管生成和血流受损：NOX1、IL-6和SASP在细胞衰老传播中的相互作用