Broussoflavonol B induces S-phase arrest and apoptosis in pancreatic cancer cells by modulating the cell cycle checkpoint through inhibition of the AURKA/PLK1 pathway.
Broussoflavonol B 通过抑制 AURKA/PLK1 通路调节细胞周期检查点,从而诱导胰腺癌细胞发生 S 期停滞和凋亡
期刊:Cancer Cell International
影响因子:6
doi:10.1186/s12935-025-03717-x
Choe HyokChol, Wang Zhen, Huang Jianhua, Yang Yutong, Zhao Zhihao, Jo HyonSu, Pak HyonU, Ali Tanveer, Ding Kaiyue, Ma Junnan, Li Lingzhi, Shang Dong, Zhang Lin