日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Dissecting the molecular determinants of clinical PARP1 inhibitor selectivity for tankyrase1

剖析临床 PARP1 抑制剂对 tankyrase1 选择性的分子决定因素

Kevin Ryan, Ben Bolaňos, Marissa Smith, Prakash B Palde, Paulina Delgado Cuenca, Todd L VanArsdale, Sherry Niessen, Lianglin Zhang, Douglas Behenna, Martha A Ornelas, Khanh T Tran, Stephen Kaiser, Lawrence Lum, Al Stewart, Ketan S Gajiwala

Molecular Basis for Redox Activation of Epidermal Growth Factor Receptor Kinase

表皮生长因子受体激酶氧化还原激活的分子基础

Truong, Thu H; Ung, Peter Man-Un; Palde, Prakash B; Paulsen, Candice E; Schlessinger, Avner; Carroll, Kate S

First-in-Class Inhibitors of Sulfur Metabolism with Bactericidal Activity against Non-Replicating M. tuberculosis

具有针对非复制型结核分枝杆菌的杀菌活性的首创硫代谢抑制剂

Prakash B Palde, Ashima Bhaskar, Laura E Pedró Rosa, Franck Madoux, Peter Chase, Vinayak Gupta, Timothy Spicer, Louis Scampavia, Amit Singh, Kate S Carroll

Functional Site Discovery in a Sulfur Metabolism Enzyme by Using Directed Evolution

利用定向进化技术发现硫代谢酶中的功能位点

Paritala, Hanumantharao; Palde, Prakash B; Carroll, Kate S

A universal entropy-driven mechanism for thioredoxin-target recognition

一种通用的熵驱动机制,用于硫氧还蛋白-靶标识别

Palde, Prakash B; Carroll, Kate S

Strategies for recognition of stem-loop RNA structures by synthetic ligands: application to the HIV-1 frameshift stimulatory sequence

合成配体识别茎环 RNA 结构的策略:应用于 HIV-1 移码刺激序列

Prakash B Palde, Leslie O Ofori, Peter C Gareiss, Jaclyn Lerea, Benjamin L Miller

Dynamic combinatorial selection of molecules capable of inhibiting the (CUG) repeat RNA-MBNL1 interaction in vitro: discovery of lead compounds targeting myotonic dystrophy (DM1)

动态组合筛选能够抑制体外 (CUG) 重复 RNA-MBNL1 相互作用的分子:发现靶向强直性肌营养不良症 (DM1) 的先导化合物

Gareiss, Peter C; Sobczak, Krzysztof; McNaughton, Brian R; Palde, Prakash B; Thornton, Charles A; Miller, Benjamin L