Palenca相关文献与解析，生知库 | 链接生命科学的每一步

Intranasal administration of Escherichia coli Nissle expressing the spike protein of SARS-CoV-2 induces long-term immunization and prevents spike protein-mediated lung injury in mice

经鼻腔给药表达 SARS-CoV-2 刺突蛋白的大肠杆菌 Nissle 可在小鼠中诱导长期免疫并预防刺突蛋白介导的肺损伤

doi:10.1016/j.biopha.2024.116441

Giovanni Sarnelli, Alessandro Del Re, Irene Palenca, Silvia Basili Franzin, Jie Lu, Luisa Seguella, Aurora Zilli, Marcella Pesce, Sara Rurgo, Giovanni Esposito, Walter Sanseverino, Giuseppe Esposito

Miconazole-like Scaffold is a Promising Lead for Naegleria fowleri-Specific CYP51 Inhibitors

咪康唑类骨架是针对福氏耐格里阿米巴原虫的CYP51特异性抑制剂的有前景的先导化合物

期刊:Journal of Medicinal Chemistry

影响因子:6.8

doi:10.1021/acs.jmedchem.3c01898

Sharma, Vandna; Madia, Valentina Noemi; Tudino, Valeria; Nguyen, Jennifer V; Debnath, Anjan; Messore, Antonella; Ialongo, Davide; Patacchini, Elisa; Palenca, Irene; Basili Franzin, Silvia; Seguella, Luisa; Esposito, Giuseppe; Petrucci, Rita; Di Matteo, Paola; Bortolami, Martina; Saccoliti, Francesco; Di Santo, Roberto; Scipione, Luigi; Costi, Roberta; Podust, Larissa M

发表日期：2023

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Intrarectal Administration of Adelmidrol plus Hyaluronic Acid Gel Ameliorates Experimental Colitis in Mice and Inhibits Pro-Inflammatory Response in Ex Vivo Cultured Biopsies Derived from Ulcerative Colitis-Affected Patients

直肠内给予阿德米德罗加透明质酸凝胶可改善小鼠实验性结肠炎，并抑制溃疡性结肠炎患者离体培养活检组织中的促炎反应。

期刊:International Journal of Molecular Sciences

影响因子:4.9

doi:10.3390/ijms25010165

Palenca, Irene; Seguella, Luisa; Zilli, Aurora; Basili Franzin, Silvia; Del Re, Alessandro; Pepi, Federico; Troiani, Anna; Pesce, Marcella; Rurgo, Sara; De Palma, Fatima Domenica Elisa; Luglio, Gaetano; Tropeano, Francesca Paola; Sarnelli, Giovanni; Esposito, Giuseppe

Oral Immunization with Escherichia coli Nissle 1917 Expressing SARS-CoV-2 Spike Protein Induces Mucosal and Systemic Antibody Responses in Mice

口服免疫表达 SARS-CoV-2 刺突蛋白的大肠杆菌 Nissle 1917 可在小鼠中诱导粘膜和全身抗体反应

期刊:Biomolecules

影响因子:4.8

doi:10.3390/biom13030569

Giovanni Sarnelli, Alessandro Del Re, Marcella Pesce, Jie Lu, Giovanni Esposito, Walter Sanseverino, Chiara Corpetti, Silvia Basili Franzin, Luisa Seguella, Irene Palenca, Sara Rurgo, Fatima Domenica Elisa De Palma, Aurora Zilli, Giuseppe Esposito

Next-Generation Probiotics for Inflammatory Bowel Disease

用于治疗炎症性肠病的下一代益生菌

期刊:International Journal of Molecular Sciences

影响因子:4.9

doi:10.3390/ijms23105466

Pesce, Marcella; Seguella, Luisa; Del Re, Alessandro; Lu, Jie; Palenca, Irene; Corpetti, Chiara; Rurgo, Sara; Sanseverino, Walter; Sarnelli, Giovanni; Esposito, Giuseppe

N-Palmitoyl-D-Glucosamine Inhibits TLR-4/NLRP3 and Improves DNBS-Induced Colon Inflammation through a PPAR-α-Dependent Mechanism

N-棕榈酰-D-葡萄糖胺通过 PPAR-α 依赖机制抑制 TLR-4/NLRP3 并改善 DNBS 诱导的结肠炎症

期刊:Biomolecules

影响因子:4.8

doi:10.3390/biom12081163

Irene Palenca, Luisa Seguella, Alessandro Del Re, Silvia Basili Franzin, Chiara Corpetti, Marcella Pesce, Sara Rurgo, Luca Steardo, Giovanni Sarnelli, Giuseppe Esposito

免疫

肠炎

Immunology/Inflammation

发表日期：2022

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Cannabidiol inhibits SARS-Cov-2 spike (S) protein-induced cytotoxicity and inflammation through a PPARÎ³-dependent TLR4/NLRP3/Caspase-1 signaling suppression in Caco-2 cell line.

大麻二酚通过抑制 PPARγ 依赖的 TLR4/NLRP3/Caspase-1 信号通路，抑制 Caco-2 细胞系中 SARS-CoV-2 刺突蛋白 (S) 诱导的细胞毒性和炎症

期刊:Phytotherapy Research

影响因子:6.3

doi:10.1002/ptr.7302

Corpetti Chiara, Del Re Alessandro, Seguella Luisa, Palenca Irene, Rurgo Sara, De Conno Barbara, Pesce Marcella, Sarnelli Giovanni, Esposito Giuseppe

Palmitoylethanolamide for Nickel Allergy: Plausible, Untested, and Worth Considering

棕榈酰乙醇胺治疗镍过敏：可能有效，但未经检验，值得考虑

Intranasal administration of Escherichia coli Nissle expressing the spike protein of SARS-CoV-2 induces long-term immunization and prevents spike protein-mediated lung injury in mice

经鼻腔给药表达 SARS-CoV-2 刺突蛋白的大肠杆菌 Nissle 可在小鼠中诱导长期免疫并预防刺突蛋白介导的肺损伤

Miconazole-like Scaffold is a Promising Lead for Naegleria fowleri-Specific CYP51 Inhibitors

咪康唑类骨架是针对福氏耐格里阿米巴原虫的CYP51特异性抑制剂的有前景的先导化合物

Intrarectal Administration of Adelmidrol plus Hyaluronic Acid Gel Ameliorates Experimental Colitis in Mice and Inhibits Pro-Inflammatory Response in Ex Vivo Cultured Biopsies Derived from Ulcerative Colitis-Affected Patients

直肠内给予阿德米德罗加透明质酸凝胶可改善小鼠实验性结肠炎，并抑制溃疡性结肠炎患者离体培养活检组织中的促炎反应。

Oral Immunization with Escherichia coli Nissle 1917 Expressing SARS-CoV-2 Spike Protein Induces Mucosal and Systemic Antibody Responses in Mice

口服免疫表达 SARS-CoV-2 刺突蛋白的大肠杆菌 Nissle 1917 可在小鼠中诱导粘膜和全身抗体反应

Next-Generation Probiotics for Inflammatory Bowel Disease

用于治疗炎症性肠病的下一代益生菌

N-Palmitoyl-D-Glucosamine Inhibits TLR-4/NLRP3 and Improves DNBS-Induced Colon Inflammation through a PPAR-α-Dependent Mechanism

N-棕榈酰-D-葡萄糖胺通过 PPAR-α 依赖机制抑制 TLR-4/NLRP3 并改善 DNBS 诱导的结肠炎症

Cannabidiol inhibits SARS-Cov-2 spike (S) protein-induced cytotoxicity and inflammation through a PPARÎ³-dependent TLR4/NLRP3/Caspase-1 signaling suppression in Caco-2 cell line.

大麻二酚通过抑制 PPARγ 依赖的 TLR4/NLRP3/Caspase-1 信号通路，抑制 Caco-2 细胞系中 SARS-CoV-2 刺突蛋白 (S) 诱导的细胞毒性和炎症