A novel mode of protein kinase inhibition exploiting hydrophobic motifs of autoinhibited kinases: discovery of ATP-independent inhibitors of fibroblast growth factor receptor.
利用自身抑制激酶的疏水基序的新型蛋白激酶抑制模式:发现成纤维细胞生长因子受体的 ATP 非依赖性抑制剂
期刊:Journal of Biological Chemistry
影响因子:3.9
doi:10.1074/jbc.M110.213736
Eathiraj Sudharshan, Palma Rocio, Hirschi Marscha, Volckova Erika, Nakuci Enkeleda, Castro Jennifer, Chen Chang-Rung, Chan Thomas C K, France Dennis S, Ashwell Mark A