日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Phosphate sensitivity of KPC-2: a hidden variable in β-lactamase kinetics

KPC-2的磷酸盐敏感性：β-内酰胺酶动力学中的一个隐藏变量

期刊:Antimicrobial Agents and Chemotherapy
影响因子:4.5
doi:10.1128/aac.01069-25
Ngango, Dignite F; Birgy, André; Palzkill, Timothy
发表日期：2026
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Norovirus replication, host interactions and vaccine advances

诺如病毒复制、宿主相互作用和疫苗进展

期刊:Nature Reviews Microbiology
影响因子:103.3
doi:10.1038/s41579-024-01144-9
Prasad, B V Venkataram; Atmar, Robert L; Ramani, Sasirekha; Palzkill, Timothy; Song, Yongcheng; Crawford, Sue E; Estes, Mary K
微生物学
发表日期：2025
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A β-lactamase inhibitory protein mutant displays high potency and a broad inhibition profile due to an altered binding mode with β-lactamases

由于与β-内酰胺酶的结合模式发生改变，一种β-内酰胺酶抑制蛋白突变体表现出高效力和广泛的抑制谱。

期刊:Journal of Biological Chemistry
影响因子:3.9
doi:10.1016/j.jbc.2025.110850
Rivera, Paola; Lu, Shuo; Ngango, Dignite; Sankaran, Banumathi; Venkataram Prasad, Bidadi; Palzkill, Timothy
发表日期：2025
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Conformational flexibility is a critical factor in designing broad-spectrum human norovirus protease inhibitors

构象灵活性是设计广谱人诺如病毒蛋白酶抑制剂的关键因素。

期刊:Journal of Virology
影响因子:3.8
doi:10.1128/jvi.01757-24
Pham, Son; Zhao, Boyang; Neetu, Neetu; Sankaran, Banumathi; Patil, Ketki; Ramani, Sasirekha; Song, Yongcheng; Estes, Mary K; Palzkill, Timothy; Prasad, B V Venkataram
微生物学
发表日期：2025
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Network of epistatic interactions in an enzyme active site revealed by large-scale deep mutational scanning

大规模深度突变扫描揭示酶活性位点上位性相互作用网络

期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.2313513121
Judge, Allison; Sankaran, Banumathi; Hu, Liya; Palaniappan, Murugesan; Birgy, André; Prasad, B V Venkataram; Palzkill, Timothy
发表日期：2024
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Expanding Complex Morpholines Using Systematic Chemical Diversity

利用系统化学多样性扩展复杂吗啉

期刊:Organic Letters
影响因子:5
doi:10.1021/acs.orglett.4c00528
Tang, Sunny Ann; Fults, Afton; Boyd, Shelton R; Gattu, Nikhil; Tran, Kevin A; Fan, Jiayi; MacKenzie, Kevin R; Palzkill, Timothy; Young, Damian W; Chamakuri, Srinivas
发表日期：2024
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The mechanism of ceftazidime and cefiderocol hydrolysis by D179Y variants of KPC carbapenemases is similar and involves the formation of a long-lived covalent intermediate

KPC碳青霉烯酶D179Y变体水解头孢他啶和头孢地洛的机制相似，均涉及长寿命共价中间体的形成。

期刊:Antimicrobial Agents and Chemotherapy
影响因子:4.5
doi:10.1128/aac.01108-23
Birgy, Andre; Nnabuife, Christina; Palzkill, Timothy
发表日期：2024
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Klebsiella pneumoniae carbapenemase variant 44 acquires ceftazidime-avibactam resistance by altering the conformation of active-site loops

肺炎克雷伯菌碳青霉烯酶变体44通过改变活性位点环的构象获得头孢他啶-阿维巴坦耐药性

期刊:Journal of Biological Chemistry
影响因子:3.9
doi:10.1016/j.jbc.2023.105493
Sun, Zhizeng; Lin, Hanfeng; Hu, Liya; Neetu, Neetu; Sankaran, Banumathi; Wang, Jin; Prasad, B V Venkataram; Palzkill, Timothy
肺炎
发表日期：2024
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CONFORMATIONAL FLEXIBILITY IS A CRITICAL FACTOR IN DESIGNING BROAD-SPECTRUM HUMAN NOROVIRUS PROTEASE INHIBITORS

构象灵活性是设计广谱人诺如病毒蛋白酶抑制剂的关键因素

期刊:
影响因子:
doi:10.1101/2024.09.16.613336
Pham, Son; Zhao, Boyang; Neetu, Neetu; Sankaran, Banumathi; Patil, Ketki; Ramani, Sasirekha; Song, Yongcheng; Estes, Mary K; Palzkill, Timothy; Prasad, B V Venkataram
微生物学
发表日期：2024
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Structural biology of MCR-1-mediated resistance to polymyxin antibiotics

MCR-1介导的多粘菌素类抗生素耐药性的结构生物学

期刊:Current Opinion in Structural Biology
影响因子:7
doi:10.1016/j.sbi.2023.102647
Materon, Isabel Cristina; Palzkill, Timothy
MCR
发表日期：2023
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