日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Application of a high-density microelectrode array assay using a 3D human iPSC-derived brain microphysiological system model for in vitro neurotoxicity screening of environmental compounds.

应用高密度微电极阵列检测技术,利用 3D 人类 iPSC 衍生脑微生理系统模型对环境化合物进行体外神经毒性筛选

Carstens Kelly E, Gronskaya Elena, Jäckel David, Bertoli Jessica, Cuevas Kelvin Ramirez, Dorier Julien, Wang Shan, Lopez-Rodriguez David, Shafer Timothy J, Zurich Marie-Gabrielle, Pamies David

Promoting reusable and open methods and protocols (PRO-MaP) can improve methodological reporting in the life sciences

推广可重复使用和开放的方法和方案(PRO-MaP)可以改善生命科学领域的方法学报告。

Batista Leite, Sofia; Brooke, Matthew A; Carusi, Annamaria; Collings, Andy; Deceuninck, Pierre; Dechamp, Jean-François; Dekker, Bronwen; De Ranieri, Elisa; Ganley, Emma; Gastaldello, Annalisa; He, Fanglian; LaFlamme, Marcel; Langezaal, Ingrid; Morris, James; Pamies, David; Piergiovanni, Monica; Pulverer, Bernd; Sadler, David; Shamu, Caroline; Siegel, Vivian; Straccia, Marco; Weissgerber, Tracey L

Taking the leap toward human-specific nonanimal methodologies: The need for harmonizing global policies for microphysiological systems

迈向以人为本的非动物研究方法:协调全球微生理系统政策的必要性

Parvatam, Surat; Pamies, David; Pistollato, Francesca; Beken, Sonja; Mariappan, Indumathi; Roth, Adrian; Piergiovanni, Monica; G C Maisonneuve, Benoît; Ewart, Lorna; Majumder, Abhijit; Dandekar, Prajakta; Date, Rahul; Mahadik, Kasturi; Thiyagarajan, Saravanan; Coecke, Sandra

Recommendations on fit-for-purpose criteria to establish quality management for microphysiological systems and for monitoring their reproducibility

关于建立微生理系统质量管理体系及其可重复性监测的适用性标准的建议

Pamies, David; Ekert, Jason; Zurich, Marie-Gabrielle; Frey, Olivier; Werner, Sophie; Piergiovanni, Monica; Freedman, Benjamin S; Keong Teo, Adrian Kee; Erfurth, Hendrik; Reyes, Darwin R; Loskill, Peter; Candarlioglu, Pelin; Suter-Dick, Laura; Wang, Shan; Hartung, Thomas; Coecke, Sandra; Stacey, Glyn N; Wagegg, Beren Atac; Dehne, Eva-Maria; Pistollato, Francesca; Leist, Marcel

Novel Strategy to Assess the Neurotoxicity of Organic Solvents Such as Glycol Ethers: Protocol for Combining In Vitro and In Silico Methods With Human-Controlled Exposure Experiments

评估乙二醇醚等有机溶剂神经毒性的新策略:将体外和计算机模拟方法与人体控制暴露实验相结合的方案

Hopf, Nancy B; Suter-Dick, Laura; Huwyler, Jörg; Borgatta, Myriam; Hegg, Lucie; Pamies, David; Paschoud, Hélène; Puligilla, Ramya Deepthi; Reale, Elena; Werner, Sophie; Zurich, Marie-Gabrielle

G × E interactions as a basis for toxicological uncertainty

基因型与环境互作是毒理学不确定性的基础

Suciu, Ilinca; Pamies, David; Peruzzo, Roberta; Wirtz, Petra H; Smirnova, Lena; Pallocca, Giorgia; Hauck, Christof; Cronin, Mark T D; Hengstler, Jan G; Brunner, Thomas; Hartung, Thomas; Amelio, Ivano; Leist, Marcel

Human brain microphysiological systems in the study of neuroinfectious disorders

人脑微生理系统在神经感染性疾病研究中的应用

Barreras, Paula; Pamies, David; Hartung, Thomas; Pardo, Carlos A

Natural and synthetic nanovectors for cancer therapy

用于癌症治疗的天然和合成纳米载体

Eftekhari, Aziz; Kryschi, Carola; Pamies, David; Gulec, Sukru; Ahmadian, Elham; Janas, Dawid; Davaran, Soodabeh; Khalilov, Rovshan

Human IPSC 3D brain model as a tool to study chemical-induced dopaminergic neuronal toxicity

人类 IPSC 3D 脑模型作为研究化学物质诱导的多巴胺能神经元毒性的工具

Pamies, David; Wiersma, Daphne; Katt, Moriah E; Zhao, Liang; Burtscher, Johannes; Harris, Georgina; Smirnova, Lena; Searson, Peter C; Hartung, Thomas; Hogberg, Helena T

Towards a qAOP framework for predictive toxicology - Linking data to decisions

构建预测毒理学的qAOP框架——将数据与决策联系起来

Paini, Alicia; Campia, Ivana; Cronin, Mark T D; Asturiol, David; Ceriani, Lidia; Exner, Thomas E; Gao, Wang; Gomes, Caroline; Kruisselbrink, Johannes; Martens, Marvin; Meek, M E Bette; Pamies, David; Pletz, Julia; Scholz, Stefan; Schüttler, Andreas; Spînu, Nicoleta; Villeneuve, Daniel L; Wittwehr, Clemens; Worth, Andrew; Luijten, Mirjam