2,5-dimethylcelecoxib alleviated NK and T-cell exhaustion in hepatocellular carcinoma via the gastrointestinal microbiota-AMPK-mTOR axis
2,5-二甲基塞来昔布通过胃肠道菌群-AMPK-mTOR轴缓解肝细胞癌中的NK细胞和T细胞耗竭。
期刊:Journal for ImmunoTherapy of Cancer
影响因子:10.6
doi:10.1136/jitc-2023-006817
Pan, Banglun; Chen, Zhanfei; Zhang, Xiaoxia; Wang, Zengbin; Yao, Yuxin; Wu, Xiaoxuan; Qiu, Jiacheng; Lin, Hua; Yu, Liumin; Tu, Haijian; Tang, Nanhong
肿瘤
mTOR
T细胞
肿瘤免疫
AMPK
微生物学
肠道菌群
T细胞
细胞生物学
免疫/内分泌