Small-molecule ligands bind to a distinct pocket in Ras and inhibit SOS-mediated nucleotide exchange activity
小分子配体与Ras蛋白的特定口袋结合，抑制SOS介导的核苷酸交换活性。
期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.1116510109
Maurer, Till; Garrenton, Lindsay S; Oh, Angela; Pitts, Keith; Anderson, Daniel J; Skelton, Nicholas J; Fauber, Benjamin P; Pan, Borlan; Malek, Shiva; Stokoe, David; Ludlam, Mary J C; Bowman, Krista K; Wu, Jiansheng; Giannetti, Anthony M; Starovasnik, Melissa A; Mellman, Ira; Jackson, Peter K; Rudolph, Joachim; Wang, Weiru; Fang, Guowei
