日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Sodium valproate drives propionylation-mediated epigenetic reprogramming to enhance mesothelin CAR-T cell therapy in solid tumors

丙戊酸钠驱动丙酰化介导的表观遗传重编程，从而增强间皮素CAR-T细胞疗法在实体瘤中的疗效

期刊:Molecular Therapy
影响因子:12
doi:10.1016/j.ymthe.2025.12.021
Chen, Jiannan; Li, Wenying; Wang, Shuai; Li, Jiayi; Zhao, Lianfeng; Ao, Xudong; Wang, Wenyu; Zhu, Li; Rao, Haipeng; Xu, Shichu; Wen, Mengru; Hu, Zhigang; Pan, Feiyan; He, Lingfeng; Gu, Lili; Fang, Weijia; Xu, Shengjing; Liang, Junqing; Zhao, Peng; Chen, Haoyan; Guo, Zhigang
表观遗传
T细胞
丙酰化
T细胞
细胞生物学
免疫/内分泌
发表日期：2026
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Erythrocyte membrane-liposome coating sustains circulation stability and targeted tumor therapy of CAR-T cells

红细胞膜-脂质体包被可维持CAR-T细胞的循环稳定性并实现靶向肿瘤治疗。

期刊:Frontiers in Immunology
影响因子:5.9
doi:10.3389/fimmu.2026.1799107
Chen, Zhiying; Zhou, Muya; Li, Xiaoyu; Zhao, Yuqi; Wang, Zhengling; Hu, Jinhua; Hong, Jialu; Zhou, Shenrui; Pan, Feiyan; Hu, Zhigang; He, Lingfeng; Gao, Tao; Jiang, Xiaodong; Wang, Zhiqiang; Guo, Zhigang
肿瘤
T细胞
肿瘤免疫
T细胞
红细胞
细胞生物学
免疫/内分泌
发表日期：2026
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Identification of necrosis-related signature for predicting prognosis and immunotherapy response in gastric cancer

识别与坏死相关的特征以预测胃癌的预后和免疫治疗反应

期刊:Translational Cancer Research
影响因子:1.7
doi:10.21037/tcr-2025-1435
Zhang, Yao; Cao, Jinghao; Jin, Feifan; Lu, Yajuan; Liu, Yingchao; Deng, Aoli; Pan, Feiyan; Yang, Chen
胃癌
肿瘤
肿瘤免疫
免疫/内分泌
发表日期：2026
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APE1 inhibition-promoted pyroptosis triggers T-cell infiltration and enhances anti-tumor immunity in NSCLC

APE1抑制促进的细胞焦亡可触发T细胞浸润并增强非小细胞肺癌的抗肿瘤免疫力。

期刊:Genes and Diseases
影响因子:
doi:10.1016/j.gendis.2025.101813
Yang, Fan; Long, Kaili; Qi, Yannan; Dai, Yuwei; Pan, Feiyan; He, Lingfeng; Yang, Lindong; Guo, Zhigang; Hu, Zhigang
肺癌
肿瘤
表观遗传
T细胞
肿瘤免疫
T细胞
焦亡
细胞生物学
免疫/内分泌
发表日期：2026
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Glutamine-driven metabolic reprogramming promotes CAR-T cell function through mTOR-SREBP2 mediated HMGCS1 upregulation in ovarian cancer

谷氨酰胺驱动的代谢重编程通过 mTOR-SREBP2 介导的 HMGCS1 上调促进卵巢癌中 CAR-T 细胞的功能

期刊:Journal of Translational Medicine
影响因子:7.5
doi:10.1186/s12967-025-06853-0
Chen, Jiannan; Zhao, Lianfeng; Li, Wenying; Wang, Shuai; Li, Jiayi; Lv, Zhongyuan; Zhao, Yaoyao; Liang, Junqing; Hu, Zhigang; Pan, Feiyan; He, Lingfeng; Gu, Lili; Guo, Zhigang
肿瘤
mTOR
T细胞
肿瘤免疫
EBP
代谢
卵巢癌
代谢重编程
细胞生物学
发表日期：2025
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Oxidative Stress Regulates CDH3 Expression in Lung Cancer Cells via OGG1-Mediated SP1 Binding.

氧化应激通过 OGG1 介导的 SP1 结合调节肺癌细胞中 CDH3 的表达

期刊:Antioxidants
影响因子:6.6
doi:10.3390/antiox14030332
Ma Ying, Guo Jiarong, Xu Shichu, Hou Yanjun, Pan Feiyan, Guo Zhigang
细胞生物学
氧化应激
发表日期：2025
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CCR2/CXCR6 enhances tumor infiltration and antitumor efficacy of MSLN CAR-T cells

CCR2/CXCR6增强MSLN CAR-T细胞的肿瘤浸润和抗肿瘤疗效

期刊:Cellular and Molecular Life Sciences
影响因子:6.2
doi:10.1007/s00018-025-05972-7
Zhang, Yan; Zhao, Lianfeng; Liu, Jiaqi; Yang, Xinhao; Chen, Tianyu; Chen, Zhengliang; Li, Wenying; Hu, Zhigang; Pan, Feiyan; Chen, Jiannan; He, Lingfeng; Guo, Zhigang
CR2
肿瘤
T细胞
肿瘤免疫
多发性硬化症
T细胞
细胞生物学
免疫/内分泌
发表日期：2025
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m6A methyltransferase METTL3 promotes non-small-cell lung carcinoma progression by inhibiting the RIG-I-MAVS innate immune pathway.

m6A 甲基转移酶 METTL3 通过抑制 RIG-I-MAVS 先天免疫途径促进非小细胞肺癌的进展

期刊:Translational Oncology
影响因子:4.1
doi:10.1016/j.tranon.2024.102230
Huang Tinghui, Ao Xudong, Liu Jie, Sun Chuancheng, Dong Yunfei, Yin Xuechen, Zhang Yan, Wang Xinping, Li Wenying, Cao Jiujiu, Pan Feiyan, Hu Zhigang, Guo Zhigang, He Lingfeng
细胞生物学
m6A/m5C/m7G
发表日期：2025
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Risk factors of thrombocytopenia in adults receiving extracorporeal membrane oxygenation support: A single center retrospective cohort study

接受体外膜肺氧合（ECMO）支持的成年患者血小板减少症的危险因素：一项单中心回顾性队列研究

期刊:Science Progress
影响因子:2.9
doi:10.1177/00368504251385949
Tong, Hongjie; Yao, Jiali; Pan, Feiyan; Wang, Kaixuan; Jinjin, Jin; Wang, Qianqian; Chen, Kun
血小板
信号转导
Adhesion/ECM
发表日期：2025
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Effect of prone positioning on survival in adult patients receiving venovenous extracorporeal membrane oxygenation for acute respiratory distress syndrome: a prospective multicenter randomized controlled study

俯卧位对接受静脉-静脉体外膜肺氧合治疗急性呼吸窘迫综合征成年患者生存率的影响：一项前瞻性多中心随机对照研究

期刊:Journal of Thoracic Disease
影响因子:1.9
doi:10.21037/jtd-23-1808
Tong, Hongjie; Pan, Feiyan; Zhang, Xiaoling; Jia, Shengwei; Vashisht, Rishik; Chen, Kun; Wang, Qianqian
发表日期：2024
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