日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

FBXO22 inhibits colitis and colorectal carcinogenesis by regulating the degradation of the S2448-phosphorylated form of mTOR

FBXO22通过调节mTOR S2448磷酸化形式的降解来抑制结肠炎和结直肠癌的发生。

期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.2402035121
Li, Minle; Chen, Xuan; Qu, Pengfei; Shao, Zhiying; Shi, Lei; Quan, Haoyu; Zhao, Xue; Xu, Jian; Shi, Luling; Chen, Silu; Zheng, Junnian; Pan, Zhen-Qiang; Bai, Jin
肿瘤
肠癌
肠炎
肿瘤免疫
mTOR
信号转导
磷酸化
结肠炎
发表日期：2024
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Modulation of Cullin-RING E3 ubiquitin ligase-dependent ubiquitination by small molecule compounds

小分子化合物对 Cullin-RING E3 泛素连接酶依赖性泛素化的调节

期刊:Journal of Biological Chemistry
影响因子:3.9
doi:10.1016/j.jbc.2024.105752
Wu, Kenneth; DeVita, Robert J; Pan, Zhen-Qiang
泛素化
表观遗传
发表日期：2024
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CRL4b Inhibition Ameliorates Experimental Autoimmune Encephalomyelitis Progression.

CRL4b抑制可改善实验性自身免疫性脑脊髓炎的进展

期刊:Journal of Immunology
影响因子:3.4
doi:10.4049/jimmunol.2300754
Dar Asif A, Ortega Yohaniz, Aktas Sera, Wu Kenneth, Guha Ipsita, Porter Nadia, Rosen Siera, DeVita Robert J, Pan Zhen-Qiang, Oliver Paula M
炎症/感染
脑炎
炎症
发表日期：2024
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Inhibitors of cullin-RING E3 ubiquitin ligase 4 with antitumor potential

具有抗肿瘤潜力的 cullin-RING E3 泛素连接酶 4 抑制剂

期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.2007328118
Wu, Kenneth; Huynh, Khoi Q; Lu, Iris; Moustakim, Moses; Miao, Haibin; Yu, Clinton; Haeusgen, Matthew J; Hopkins, Benjamin D; Huang, Lan; Zheng, Ning; Sanchez, Roberto; DeVita, Robert J; Pan, Zhen-Qiang
肿瘤
肿瘤免疫
发表日期：2021
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A Novel Strategy to Track Lysine-48 Ubiquitination by Fluorescence Resonance Energy Transfer

一种利用荧光共振能量转移追踪赖氨酸48泛素化的新策略

期刊:Methods in Molecular Biology
影响因子:
doi:10.1007/978-1-0716-1217-0_7
Wu, Kenneth; Pan, Zhen-Qiang
IF
泛素化
表观遗传
发表日期：2021
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Methylation of EZH2 by PRMT1 regulates its stability and promotes breast cancer metastasis

PRMT1介导的EZH2甲基化调节其稳定性并促进乳腺癌转移

期刊:Cell Death and Differentiation
影响因子:15.4
doi:10.1038/s41418-020-00615-9
Li, Zhongwei; Wang, Diandian; Lu, Jun; Huang, Baiqu; Wang, Yibo; Dong, Meichen; Fan, Dongmei; Li, Hongyuan; Gao, Yanyan; Hou, Pingfu; Li, Minle; Liu, Hui; Pan, Zhen-Qiang; Zheng, Junnian; Bai, Jin
肿瘤
表观遗传
肿瘤免疫
PRMT1
乳腺癌
EZH2
DNA甲基化
发表日期：2020
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IKK-Mediated Regulation of the COP9 Signalosome via Phosphorylation of CSN5

IKK介导的COP9信号体调控是通过CSN5的磷酸化实现的

期刊:Journal of Proteome Research
影响因子:3.6
doi:10.1021/acs.jproteome.9b00626
Zhang, Jingzi; Zhao, Ruoyu; Yu, Clinton; Bryant, Christine L N; Wu, Kenneth; Liu, Zhihong; Ding, Yibing; Zhao, Yue; Xue, Bin; Pan, Zhen-Qiang; Li, Chaojun; Huang, Lan; Fang, Lei
信号转导
CSN5
磷酸化
发表日期：2020
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Cullin-RING E3 Ubiquitin Ligase 7 in Growth Control and Cancer

Cullin-RING E3泛素连接酶7在生长控制和癌症中的作用

期刊:Advances in Experimental Medicine and Biology
影响因子:
doi:10.1007/978-981-15-1025-0_17
Pan, Zhen-Qiang
肿瘤
肿瘤免疫
发表日期：2020
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SCF(FBXO22) targets HDM2 for degradation and modulates breast cancer cell invasion and metastasis

SCF(FBXO22)靶向HDM2进行降解，并调节乳腺癌细胞的侵袭和转移。

期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.1820990116
Bai, Jin; Wu, Kenneth; Cao, Meng-Han; Yang, Yingying; Pan, Yu; Liu, Hui; He, Yizhou; Itahana, Yoko; Huang, Lan; Zheng, Jun-Nian; Pan, Zhen-Qiang
肿瘤
肿瘤免疫
乳腺癌
SCF
细胞生物学
发表日期：2019
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Suramin inhibits cullin-RING E3 ubiquitin ligases.

Suramin 抑制 cullin-RING E3 泛素连接酶

期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.1601089113
Wu Kenneth, Chong Robert A, Yu Qing, Bai Jin, Spratt Donald E, Ching Kevin, Lee Chan, Miao Haibin, Tappin Inger, Hurwitz Jerard, Zheng Ning, Shaw Gary S, Sun Yi, Felsenfeld Dan P, Sanchez Roberto, Zheng Jun-Nian, Pan Zhen-Qiang
信号转导
发表日期：2016
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