A new strategy for CAR-T therapy in solid tumors: IL-15-autocrine signaling augments tumor stroma depletion and promotes a T(SCM) subset in the TME.
实体瘤 CAR-T 疗法的新策略:IL-15 自分泌信号增强肿瘤基质耗竭并促进 TME 中 T(SCM) 亚群的形成。
期刊:Cell Death & Disease
影响因子:9.6
doi:10.1038/s41419-025-08405-2
Pang Yanyang, Chen Leiyuan, Sun Qinghui, He Na, Lai Zhiheng, Wang Xi, Xie Zhihao, Yang Wenli, Wang Wu