日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Effects of Cipepofol on Cardiac Depolarization and Repolarization in Healthy Subjects: A Single-Center, Randomized, Placebo and Positive-Controlled Thorough QT Study

西哌泊酚对健康受试者心脏去极化和复极化的影响：一项单中心、随机、安慰剂和阳性对照的全面QT间期研究

期刊:Drug Design Development and Therapy
影响因子:5.1
doi:10.2147/DDDT.S565051
Kleiman, Robert; Rudo, Todd; Daley, William; Hu, Mengyue; Yan, Pangke; Zhou, Rong; Hou, Jie
发表日期：2026
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Efficacy and safety of cofrogliptin once every 2 weeks in Chinese patients with type 2 diabetes: A randomized, double-blind, placebo-controlled, phase 3 trial

一项随机、双盲、安慰剂对照的3期临床试验，评估了每2周一次服用考格列汀治疗中国2型糖尿病患者的疗效和安全性。

期刊:Diabetes Obesity & Metabolism
影响因子:5.7
doi:10.1111/dom.16014
Gao, Leili; Bian, Fang; Pan, Tianrong; Jiang, Hongwei; Feng, Bo; Jiang, Chengxia; Sun, Jia; Xiao, Jianzhong; Yan, Pangke; Ji, Linong
糖尿病
代谢
发表日期：2025
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Pharmacokinetics and exposure-safety relationship of ciprofol for sedation in mechanically ventilated patients in the intensive care unit

环丙酚用于重症监护病房机械通气患者镇静的药代动力学和暴露-安全性关系

期刊:Cpt-Pharmacometrics & Systems Pharmacology
影响因子:3
doi:10.1002/psp4.13121
Liu, Lu; Wang, Kun; Sun, Zhongyi; Yan, Pangke; Hu, Mengyue; Liu, Xiao; Chen, Meixia; Wu, Nan; Xiang, Xiaoqiang
发表日期：2024
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Pharmacokinetics, pharmacodynamics, and safety of ciprofol emulsion in Chinese subjects with normal or impaired renal function

环丙酚乳剂在肾功能正常或受损的中国受试者中的药代动力学、药效学和安全性研究

期刊:Frontiers in Pharmacology
影响因子:4.8
doi:10.3389/fphar.2023.1260599
Tao, Jun; Liu, Shuaibing; Zhao, Ying Ying; Qi, Lei; Yan, Pangke; Wu, Nan; Liu, Xiao; Liu, Dongwei; Tian, Xin
发表日期：2023
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Dose decision of HSK7653 oral immediate release tablets in specific populations clinical trials based on mechanistic physiologically-based pharmacokinetic model

基于机制性生理药代动力学模型，确定特定人群临床试验中 HSK7653 口服速释片的剂量

期刊:European Journal of Pharmaceutical Sciences
影响因子:4.7
doi:10.1016/j.ejps.2023.106553
Zhang, Miao; Zhang, Shudong; Yu, Zhiheng; Yao, Xueting; Lei, Zihan; Yan, Pangke; Wu, Nan; Wang, Xu; Hu, Qin; Liu, Dongyang
发表日期：2023
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Safety, pharmacokinetics and pharmacodynamics of a novel γ-aminobutyric acid (GABA) receptor potentiator, HSK3486, in Chinese patients with hepatic impairment

本研究旨在评估一种新型γ-氨基丁酸（GABA）受体增强剂HSK3486在中国肝功能受损患者中的安全性、药代动力学和药效学。

期刊:
影响因子:
doi:10.1080/07853890.2022.2129433
Hu, Yue; Li, Xiaojiao; Liu, Jingrui; Chen, Hong; Zheng, Wenbo; Zhang, Hong; Wu, Min; Li, Cuiyun; Zhu, Xiaoxue; Lou, Jinfeng; Yan, Pangke; Wu, Nan; Liu, Xiao; Ma, Shiping; Wang, Xu; Ding, Yanhua; Xuan, Chengluan
信号转导
发表日期：2022
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