日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Mechanism of beta-arrestin 1 mediated Src activation via Src SH3 domain revealed by cryo-electron microscopy.

冷冻电镜揭示了β-arrestin 1通过Src SH3结构域介导Src激活的机制。

期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-026-69884-1
Pakharukova Natalia, Thomas Brittany N, Bansia Harsh, Li Linus, Bassford Dana K, Abzalimov Rinat R, Kim Jihee, Kahsai Alem W, Pani Biswaranjan, Xiao Kunhong, Ochakovski Roni, Liu Shibo, Zhang Xingdong, Ahn Seungkirl, des Georges Amedee, Lefkowitz Robert J
SRC
REST
发表日期：2026
文献求助 收藏

β-Arrestin Condensates Regulate G Protein-Coupled Receptor Function

β-arrestin 凝聚体调节 G 蛋白偶联受体功能

期刊:
影响因子:
doi:10.1101/2025.04.05.647240
Anderson, Preston J; Xiao, Peng; Zhong, Yani; Kaakati, Adam; Alfonso-DeSouza, Juliana; Zhang, Tianyao; Zhang, Chao; Yu, Kevin; Qi, Lei; Ding, Wei; Liu, Samuel; Pani, Biswaranjan; Krishnan, Athmika; Chen, Oscar; Jassal, Chanpreet; Strawn, Joseph; Sun, Jin-Peng; Rajagopal, Sudarshan
信号转导
发表日期：2025
文献求助 收藏

How carvedilol does not activate β(2)-adrenoceptors

卡维地洛如何不激活β(2)-肾上腺素受体

期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-023-42848-5
Lefkowitz, Robert J; Rockman, Howard A; Shim, Paul J; Liu, Samuel; Ahn, Seungkirl; Pani, Biswaranjan; Rajagopal, Sudarshan; Shenoy, Sudha K; Bouvier, Michel; Benovic, Jeffrey L; Liggett, Stephen B; Ruffolo, Robert R; Bristow, Michael R; Packer, Milton
信号转导
免疫/内分泌
发表日期：2023
文献求助 收藏

β-Arrestin-Biased Allosteric Modulator Potentiates Carvedilol-Stimulated β Adrenergic Receptor Cardioprotection

β-arrestin偏向性变构调节剂增强卡维地洛刺激的β肾上腺素能受体心脏保护作用

期刊:Molecular Pharmacology
影响因子:3
doi:10.1124/molpharm.121.000359
Wang, Jialu; Pani, Biswaranjan; Gokhan, Ilhan; Xiong, Xinyu; Kahsai, Alem W; Jiang, Haoran; Ahn, Seungkirl; Lefkowitz, Robert J; Rockman, Howard A
信号转导
免疫/内分泌
发表日期：2021
文献求助 收藏

Unique Positive Cooperativity Between the β-Arrestin-Biased β-Blocker Carvedilol and a Small Molecule Positive Allosteric Modulator of the β2-Adrenergic Receptor

β-阻滞剂卡维地洛与β2-肾上腺素能受体小分子正向变构调节剂之间独特的正向协同作用

期刊:Molecular Pharmacology
影响因子:3
doi:10.1124/molpharm.121.000363
Pani, Biswaranjan; Ahn, Seungkirl; Rambarat, Paula K; Vege, Shashank; Kahsai, Alem W; Liu, Andrew; Valan, Bruno N; Staus, Dean P; Costa, Tommaso; Lefkowitz, Robert J
信号转导
免疫/内分泌
发表日期：2021
文献求助 收藏

GPCR signaling: conformational activation of arrestins

GPCR信号传导：阻遏蛋白的构象激活

期刊:Cell Research
影响因子:25.9
doi:10.1038/s41422-018-0067-x
Kahsai, Alem W; Pani, Biswaranjan; Lefkowitz, Robert J
信号转导
GPCR/Calcium/cAMP
发表日期：2018
文献求助 收藏

Sortase ligation enables homogeneous GPCR phosphorylation to reveal diversity in β-arrestin coupling

Sortase连接可实现均一的GPCR磷酸化，从而揭示β-arrestin偶联的多样性

期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.1722336115
Staus, Dean P; Wingler, Laura M; Choi, Minjung; Pani, Biswaranjan; Manglik, Aashish; Kruse, Andrew C; Lefkowitz, Robert J
信号转导
磷酸化
GPCR/Calcium/cAMP
发表日期：2018
文献求助 收藏

Small-Molecule Positive Allosteric Modulators of the β(2)-Adrenoceptor Isolated from DNA-Encoded Libraries

从DNA编码文库中分离的β(2)-肾上腺素受体小分子正向变构调节剂

期刊:Molecular Pharmacology
影响因子:3
doi:10.1124/mol.118.111948
Ahn, Seungkirl; Pani, Biswaranjan; Kahsai, Alem W; Olsen, Eva K; Husemoen, Gitte; Vestergaard, Mikkel; Jin, Lei; Zhao, Shuai; Wingler, Laura M; Rambarat, Paula K; Simhal, Rishabh K; Xu, Thomas T; Sun, Lillian D; Shim, Paul J; Staus, Dean P; Huang, Li-Yin; Franch, Thomas; Chen, Xin; Lefkowitz, Robert J
信号转导
免疫/内分泌
发表日期：2018
文献求助 收藏

Mechanism of intracellular allosteric β(2)AR antagonist revealed by X-ray crystal structure.

X射线晶体结构揭示了细胞内变构β2AR拮抗剂的作用机制

期刊:Nature
影响因子:48.5
doi:10.1038/nature23652
Liu Xiangyu, Ahn Seungkirl, Kahsai Alem W, Meng Kai-Cheng, Latorraca Naomi R, Pani Biswaranjan, Venkatakrishnan A J, Masoudi Ali, Weis William I, Dror Ron O, Chen Xin, Lefkowitz Robert J, Kobilka Brian K
细胞生物学
发表日期：2017
文献求助 收藏

Neurological and Motor Disorders: Neuronal Store-Operated Ca(2+) Signaling: An Overview and Its Function

神经系统和运动障碍：神经元储存操纵型钙离子信号传导：概述及其功能

期刊:Advances in Experimental Medicine and Biology
影响因子:
doi:10.1007/978-3-319-57732-6_27
Bollimuntha, Sunitha; Pani, Biswaranjan; Singh, Brij B
信号转导
神经科学
发表日期：2017
文献求助 收藏