日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Influenza virus infection in the lungs leads to pancytopenia and defective immune cell differentiation program in the thymus and bone marrow

肺部流感病毒感染会导致全血细胞减少,并损害胸腺和骨髓中的免疫细胞分化程序。

Shinde, Prajakta; Silvestri, Giovannino; Kuppusamy, Panjamurthy; Stamatos, Nicholas; Rathinam, Chozha Vendan

Disruption of mitochondrial pyruvate oxidation in dorsal root ganglia drives persistent nociceptive sensitization and causes pervasive transcriptomic alterations

背根神经节线粒体丙酮酸氧化紊乱会导致持续性伤害性感受敏化,并引起广泛的转录组改变。

Md Mamunul Haque ,Panjamurthy Kuppusamy ,Ohannes K Melemedjian

Glutamine Oxidation in Mouse Dorsal Root Ganglia Regulates Pain Resolution and Chronification

小鼠背根神经节中谷氨酰胺氧化调节疼痛消退和慢性化

Md Mamunul Haque ,Panjamurthy Kuppusamy ,Ohannes K Melemedjian

Targeting metabolic pathways alleviates bortezomib-induced neuropathic pain without compromising anticancer efficacy in a sex-specific manner.

针对代谢途径可以缓解硼替佐米引起的神经性疼痛,且不会以性别特异性的方式影响抗癌疗效

Kuppusamy Panjamurthy, Haque Md Mamunul, Traub Richard J, Melemedjian Ohannes K

Metformin Enhances the Anti-Cancer Efficacy of Sorafenib via Suppressing MAPK/ERK/Stat3 Axis in Hepatocellular Carcinoma

二甲双胍通过抑制肝细胞癌中的 MAPK/ERK/Stat3 轴增强索拉非尼的抗癌功效

Sumit Siddharth, Panjamurthy Kuppusamy, Qitong Wu, Arumugam Nagalingam, Neeraj K Saxena, Dipali Sharma

Hyperleptinemia in obese state renders luminal breast cancers refractory to tamoxifen by coordinating a crosstalk between Med1, miR205 and ErbB

肥胖状态下的高瘦素血症通过协调 Med1、miR205 和 ErbB 之间的串扰使管腔乳腺癌对他莫昔芬产生耐药性

Arumugam Nagalingam, Sumit Siddharth #, Sheetal Parida #, Nethaji Muniraj, Dimiter Avtanski, Panjamurthy Kuppusamy, Justin Elsey, Jack L Arbiser, Balázs Győrffy, Dipali Sharma

ADIPOQ/adiponectin induces cytotoxic autophagy in breast cancer cells through STK11/LKB1-mediated activation of the AMPK-ULK1 axis

ADIPOQ/脂联素通过 STK11/LKB1 介导的 AMPK-ULK1 轴激活诱导乳腺癌细胞发生细胞毒性自噬

Seung J Chung, Ganji Purnachandra Nagaraju, Arumugam Nagalingam, Nethaji Muniraj, Panjamurthy Kuppusamy, Alyssa Walker, Juhyung Woo, Balázs Győrffy, Ed Gabrielson, Neeraj K Saxena, Dipali Sharma

Interacting post-muscarinic receptor signaling pathways potentiate matrix metalloproteinase-1 expression and invasion of human colon cancer cells

相互作用的后毒蕈碱受体信号通路增强基质金属蛋白酶-1 的表达和人类结肠癌细胞的侵袭

Anan H Said, Shien Hu, Ameer Abutaleb, Tonya Watkins, Kunrong Cheng, Ahmed Chahdi, Panjamurthy Kuppusamy, Neeraj Saxena, Guofeng Xie, Jean-Pierre Raufman

Benzyl Isothiocyanate potentiates p53 signaling and antitumor effects against breast cancer through activation of p53-LKB1 and p73-LKB1 axes

异硫氰酸苄酯通过激活 p53-LKB1 和 p73-LKB1 轴增强 p53 信号传导和抗乳腺癌肿瘤作用

Bei Xie, Arumugam Nagalingam, Panjamurthy Kuppusamy, Nethaji Muniraj, Peter Langford, Balázs Győrffy, Neeraj K Saxena, Dipali Sharma

Concomitant activation of ETS-like transcription factor-1 and Death Receptor-5 via extracellular signal-regulated kinase in withaferin A-mediated inhibition of hepatocarcinogenesis in mice

在醉茄素 A 介导的小鼠肝癌形成抑制中,ETS 样转录因子 1 和死亡受体 5 通过细胞外信号调节激酶同时激活

Panjamurthy Kuppusamy, Arumugam Nagalingam, Nethaji Muniraj, Neeraj K Saxena, Dipali Sharma