日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

PSA-Targeted Alpha-, Beta-, and Positron-Emitting Immunotheranostics in Murine Prostate Cancer Models and Nonhuman Primates

在小鼠前列腺癌模型和非人灵长类动物中,以PSA为靶点的α、β和正电子发射免疫治疗诊断技术

Veach, Darren R; Storey, Claire M; Lückerath, Katharina; Braun, Katharina; von Bodman, Christian; Lamminmäki, Urpo; Kalidindi, Teja; Strand, Sven-Erik; Strand, Joanna; Altai, Mohamed; Damoiseaux, Robert; Zanzonico, Pat; Benabdallah, Nadia; Pankov, Dmitry; Scher, Howard I; Scardino, Peter; Larson, Steven M; Lilja, Hans; McDevitt, Michael R; Thorek, Daniel L J; Ulmert, David

Epigenetic reprogramming sensitizes immunologically silent EBV+ lymphomas to virus-directed immunotherapy.

表观遗传重编程使免疫沉默的 EBV+ 淋巴瘤对病毒导向免疫疗法敏感

Dalton Tanner, Doubrovina Ekaterina, Pankov Dmitry, Reynolds Raymond, Scholze Hanna, Selvakumar Annamalai, Vizconde Teresa, Savalia Bhumesh, Dyomin Vadim, Weigel Christoph, Oakes Christopher C, Alonso Alicia, Elemento Olivier, Pan Heng, Phillip Jude M, O'Reilly Richard J, Gewurz Benjamin E, Cesarman Ethel, Giulino-Roth Lisa

Mechanisms of leukemia resistance to antibody dependent cellular cytotoxicity

白血病对抗体依赖性细胞毒性的耐药机制

Dubrovsky, Leonid; Brea, Elliott Joseph; Pankov, Dmitry; Casey, Emily; Dao, Tao; Liu, Cheng; Scheinberg, David A

T cell receptor mimic antibodies for cancer therapy

用于癌症治疗的T细胞受体模拟抗体

Dubrovsky, Leonid; Dao, Tao; Gejman, Ron S; Brea, Elliott J; Chang, Aaron Y; Oh, Claire Y; Casey, Emily; Pankov, Dmitry; Scheinberg, David A

Opportunities and challenges for TCR mimic antibodies in cancer therapy

TCR模拟抗体在癌症治疗中的机遇与挑战

Chang, Aaron Y; Gejman, Ron S; Brea, Elliott J; Oh, Claire Y; Mathias, Melissa D; Pankov, Dmitry; Casey, Emily; Dao, Tao; Scheinberg, David A

Therapeutic bispecific T-cell engager antibody targeting the intracellular oncoprotein WT1

靶向细胞内癌蛋白WT1的治疗性双特异性T细胞衔接抗体

Dao, Tao; Pankov, Dmitry; Scott, Andrew; Korontsvit, Tatyana; Zakhaleva, Victoriya; Xu, Yiyang; Xiang, Jingyi; Yan, Su; de Morais Guerreiro, Manuel Direito; Veomett, Nicholas; Dubrovsky, Leonid; Curcio, Michael; Doubrovina, Ekaterina; Ponomarev, Vladimir; Liu, Cheng; O'Reilly, Richard J; Scheinberg, David A

A small-molecule c-Rel inhibitor reduces alloactivation of T cells without compromising antitumor activity

一种小分子c-Rel抑制剂可降低T细胞的同种异体活化,且不影响其抗肿瘤活性。

Shono, Yusuke; Tuckett, Andrea Z; Ouk, Samedy; Liou, Hsiou-Chi; Altan-Bonnet, Grégoire; Tsai, Jennifer J; Oyler, Jennifer E; Smith, Odette M; West, Mallory L; Singer, Natalie V; Doubrovina, Ekaterina; Pankov, Dmitry; Undhad, Chandresh V; Murphy, George F; Lezcano, Cecilia; Liu, Chen; O'Reilly, Richard J; van den Brink, Marcel R M; Zakrzewski, Johannes L

A TCR-mimic antibody to WT1 bypasses tyrosine kinase inhibitor resistance in human BCR-ABL+ leukemias.

针对 WT1 的 TCR 模拟抗体可绕过人类 BCR-ABL+ 白血病中的酪氨酸激酶抑制剂耐药性

Dubrovsky Leonid, Pankov Dmitry, Brea Elliott Joseph, Dao Tao, Scott Andrew, Yan Su, O'Reilly Richard J, Liu Cheng, Scheinberg David A

Therapeutic efficacy of an Fc-enhanced TCR-like antibody to the intracellular WT1 oncoprotein

针对细胞内WT1癌蛋白的Fc增强型TCR样抗体的治疗效果

Veomett, Nicholas; Dao, Tao; Liu, Hong; Xiang, Jingyi; Pankov, Dmitry; Dubrovsky, Leonid; Whitten, Joseph A; Park, Sun-Mi; Korontsvit, Tatyana; Zakhaleva, Victoria; Casey, Emily; Curcio, Michael; Kharas, Michael G; O'Reilly, Richard J; Liu, Cheng; Scheinberg, David A

Targeting the intracellular WT1 oncogene product with a therapeutic human antibody

利用治疗性人源抗体靶向细胞内WT1癌基因产物

Dao, Tao; Yan, Su; Veomett, Nicholas; Pankov, Dmitry; Zhou, Liang; Korontsvit, Tatyana; Scott, Andrew; Whitten, Joseph; Maslak, Peter; Casey, Emily; Tan, Taochao; Liu, Hong; Zakhaleva, Victoria; Curcio, Michael; Doubrovina, Ekaterina; O'Reilly, Richard J; Liu, Cheng; Scheinberg, David A