日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Dependence on Mdm2 for Mdm4 inhibition of p53 activity

Mdm4对p53活性的抑制依赖于Mdm2

Xiong, Shunbin; Zhang, Yun; Zhou, Xin; Pant, Vinod; Mirani, Akshita; Gencel-Augusto, Jovanka; Chau, Gilda; You, M James; Lozano, Guillermina

Tissue specificity and spatio-temporal dynamics of the p53 transcriptional program

p53转录程序的组织特异性和时空动态

Pant, Vinod; Sun, Chang; Lozano, Guillermina

Dicer1 Phosphomimetic Promotes Tumor Progression and Dissemination

Dicer1 磷酸化物促进肿瘤进展和扩散

Aryal, Neeraj K; Pant, Vinod; Wasylishen, Amanda R; Rimel, Bobbie J; Baseler, Laura; El-Naggar, Adel K; Mutch, David G; Goodfellow, Paul J; Arur, Swathi; Lozano, Guillermina

Constitutive Dicer1 phosphorylation accelerates metabolism and aging in vivo

Dicer1 组成型磷酸化可加速体内代谢和衰老。

Aryal, Neeraj K; Pant, Vinod; Wasylishen, Amanda R; Parker-Thornburg, Jan; Baseler, Laura; El-Naggar, Adel K; Liu, Bin; Kalia, Awdhesh; Lozano, Guillermina; Arur, Swathi

Synergistic and additive effect of retinoic acid in circumventing resistance to p53 restoration

维甲酸在克服p53修复耐药性方面的协同和累加效应

Larsson, Connie A; Moyer, Sydney M; Liu, Bin; Michel, Keith A; Pant, Vinod; Yang, Peirong; Wong, Justin; El-Naggar, Adel K; Krahe, Ralf; Lozano, Guillermina

The p53 inhibitor Mdm4 cooperates with multiple genetic lesions in tumourigenesis

p53抑制剂Mdm4与多种基因损伤协同作用,参与肿瘤发生。

Xiong, Shunbin; Pant, Vinod; Zhang, Yun; Aryal, Neeraj K; You, M James; Kusewitt, Donna; Lozano, Guillermina

TRIM24 suppresses development of spontaneous hepatic lipid accumulation and hepatocellular carcinoma in mice

TRIM24抑制小鼠自发性肝脏脂质积累和肝细胞癌的发生发展

Jiang, Shiming; Minter, Lindsey Cauthen; Stratton, Sabrina A; Yang, Peirong; Abbas, Hussein A; Akdemir, Zeynep Coban; Pant, Vinod; Post, Sean; Gagea, Mihai; Lee, Richard G; Lozano, Guillermina; Barton, Michelle Craig

Limiting the power of p53 through the ubiquitin proteasome pathway

通过泛素-蛋白酶体途径限制p53的活性

Pant, Vinod; Lozano, Guillermina

Dissecting the p53-Mdm2 feedback loop in vivo: uncoupling the role in p53 stability and activity.

剖析体内 p53-Mdm2 反馈回路:解耦 p53 稳定性和活性中的作用

Pant Vinod, Lozano Guillermina

Heterodimerization of Mdm2 and Mdm4 is critical for regulating p53 activity during embryogenesis but dispensable for p53 and Mdm2 stability.

Mdm2 和 Mdm4 的异二聚化对于胚胎发生过程中调节 p53 活性至关重要,但对于 p53 和 Mdm2 的稳定性并非必需

Pant Vinod, Xiong Shunbin, Iwakuma Tomoo, Quintás-Cardama Alfonso, Lozano Guillermina