日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

The Role of Signaling Pathways of Inflammation and Oxidative Stress in Development of Senescence and Aging Phenotypes in Cardiovascular Disease

炎症和氧化应激信号通路在心血管疾病衰老表型发展中的作用

Papaconstantinou, John

8-Oxoguanine DNA glycosylase1-driven DNA repair-A paradoxical role in lung aging

8-氧鸟嘌呤DNA糖基化酶1驱动的DNA修复——在肺衰老中发挥矛盾作用

German, Peter; Saenz, David; Szaniszlo, Peter; Aguilera-Aguirre, Leopoldo; Pan, Lang; Hegde, Muralidhar L; Bacsi, Attila; Hajas, Gyorgy; Radak, Zsolt; Ba, Xueqing; Mitra, Sankar; Papaconstantinou, John; Boldogh, Istvan

Klotho Protects Dopaminergic Neuron Oxidant-Induced Degeneration by Modulating ASK1 and p38 MAPK Signaling Pathways

Klotho通过调节ASK1和p38 MAPK信号通路保护多巴胺能神经元免受氧化剂诱导的退化

Brobey, Reynolds K; German, Dwight; Sonsalla, Patricia K; Gurnani, Prem; Pastor, Johanne; Hsieh, C-C; Papaconstantinou, John; Foster, Philip P; Kuro-o, Makoto; Rosenblatt, Kevin P

IGF-1 mediated phosphorylation of specific IRS-1 serines in Ames dwarf fibroblasts is associated with longevity

IGF-1介导的Ames矮小动物成纤维细胞中特定IRS-1丝氨酸的磷酸化与长寿相关

Papaconstantinou, John; Hsieh, Ching-Chyuan

Ishemia-reperfusion enhances GAPDH nitration in aging skeletal muscle

缺血再灌注增强衰老骨骼肌中GAPDH的硝化作用

Bailey, C Eric; Hammers, David W; Deford, James H; Dimayuga, Vincent L; Amaning, James K; Farrar, Roger; Papaconstantinou, John

Intestinal mitochondrial apoptotic signaling is activated during oxidative stress

氧化应激期间,肠道线粒体凋亡信号通路被激活。

Baregamian, Naira; Song, Jun; Papaconstantinou, John; Hawkins, Hal K; Evers, B Mark; Chung, Dai H

The ASK1-Signalosome regulates p38 MAPK activity in response to levels of endogenous oxidative stress in the Klotho mouse models of aging.

在 Klotho 小鼠衰老模型中,ASK1-信号体调节 p38 MAPK 活性以响应内源性氧化应激水平

Hsieh C-C, Kuro-o Makoto, Rosenblatt Kevin P, Brobey Reynolds, Papaconstantinou John

Insulin/IGF-1 and ROS signaling pathway cross-talk in aging and longevity determination

胰岛素/IGF-1和ROS信号通路在衰老和寿命决定中的相互作用

Papaconstantinou, John

Tumor necrosis factor-alpha and apoptosis signal-regulating kinase 1 control reactive oxygen species release, mitochondrial autophagy, and c-Jun N-terminal kinase/p38 phosphorylation during necrotizing enterocolitis

肿瘤坏死因子-α和凋亡信号调节激酶1在坏死性小肠结肠炎中控制活性氧释放、线粒体自噬和c-Jun N端激酶/p38磷酸化。

Baregamian, Naira; Song, Jun; Bailey, C Eric; Papaconstantinou, John; Evers, B Mark; Chung, Dai H

Decreased enzyme activities of chaperones PDI and BiP in aged mouse livers

老年小鼠肝脏中分子伴侣PDI和BiP的酶活性降低

Nuss, Jonathan E; Choksi, Kashyap B; DeFord, James H; Papaconstantinou, John