SARS-CoV-2 infects human brain organoids causing cell death and loss of synapses that can be rescued by treatment with Sofosbuvir
SARS-CoV-2 会感染人脑类器官,导致细胞死亡和突触丢失,而索非布韦治疗可以挽救这些损伤。
期刊:PLoS Biology
影响因子:7.8
doi:10.1371/journal.pbio.3001845
Pinar Mesci,Janaina S de Souza,Laura Martin-Sancho,Angela Macia,Aurian Saleh,Xin Yin,Cedric Snethlage,Jason W Adams,Simoni H Avansini,Roberto H Herai,Angels Almenar-Queralt,Yuan Pu,Ryan A Szeto,Gabriela Goldberg,Patrick T Bruck,Fabio Papes,Sumit K Chanda,Alysson R Muotri
新冠
Human
细胞生物学
SARS-CoV-2
3D/类器官